Results 221 to 230 of about 29,463 (289)

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

IGZO-Based Electronic Device Application: Advancements in Gas Sensor, Logic Circuit, Biosensor, Neuromorphic Device, and Photodetector Technologies. [PDF]

Micromachines (Basel)
Han Y, Seo J, Lee DH, Yoo H.
europepmc   +1 more source

Group Agency and Egalitarian Corporate Structure: The Epistemic, Incentive, and Control Dimensions

Journal of Applied Philosophy, EarlyView.
ABSTRACT What constitutes a good corporate agent? The article answers this question by critically applying List and Pettit's theory of group agency, which emphasizes three crucial dimensions of organizational design: epistemic quality, incentive compatibility, and control.
Chi Kwok, Chris Man‐Kong Li
wiley   +1 more source

Enhanced CPU Design for SDN Controller. [PDF]

Micromachines (Basel)
Bazzi HS, Jaber RA, El-Hajj AM, Hija FA, Haidar AM.   +4 more
europepmc   +1 more source

Internationalization, Dynamic Capabilities, and Innovation: Unveiling the Impact on Hotel Chain Performance

Strategic Change, EarlyView.
ABSTRACT The indirect effect of dynamic capabilities on performance has recently emerged as a topic of significant interest and debate in management research. In turbulent environments such as the international hotel industry, where companies constantly innovate to improve their performance, it is important to consider the effect of these dynamic ...
Laura Rienda, Rosario Andreu, Lorena Ruiz‐Fernández   +2 more
wiley   +1 more source

NXT007 enhances <i>in vitro</i> coagulation potential in the coexistence of emicizumab in hemophilia A through distinct complex formation. [PDF]

Res Pract Thromb Haemost
Yamaguchi K, Haraya K, Koga H, Nishimura K, Inaba K, Muraoka M, Muto A, Kitazawa T.   +7 more
europepmc   +1 more source

EQUATIONAL COMPLETENESS CRITERION IN TERNARY LOGIC

University proceedings. Volga region. Physical and mathematical sciences, 2019
openaire   +1 more source

Structural and functional insights into internal domain replacement in SpCas9 for protein engineering. [PDF]

Sci Rep
Kim S, Won H, Bae J, Kim J, Choi J, Richar H, Kim YG, Choi HJ.   +7 more
europepmc   +1 more source

Cellulose Nanocrystals for Advanced Optics and Electronics: Current Status and Future Directions. [PDF]

Micromachines (Basel)
Jeon H, Oh KK, Kim M.
europepmc   +1 more source