Results 51 to 60 of about 67,544 (332)

Regioselective Hydration of Terpenes with Cofactor‐Independent Carotenoid 1,2‐Hydratase

Angewandte Chemie, EarlyView.
This study reveals a highly regioselective and cofactor‐independent enzymatic approach to terpene and terpenoid hydration using a carotenoid 1,2‐hydratase from Rubrivivax gelatinosus. Beyond detailing reaction optimization strategies, an extensive substrate scope, and scale‐up potential, it explores mutagenesis and structural modeling to identify key ...
Philip Horz, Natalie Härterich, Andreas Schneider, Nicolas D. Travnicek, Bettina M. Nestl, Ursula Kahler, Bernhard Hauer   +6 more
wiley   +2 more sources

Comparative transcriptomic and metabonomic analysis revealed the relationships between biosynthesis of volatiles and flavonoid metabolites in Rosa rugosa

Ornamental Plant Research, 2021
Rosa rugosa is not only cultivated as a landscaping plant, but also used in cosmetics, the medical and food industries. However, little information is currently available on the gene regulatory networks involved in its scent and color biosynthesis and ...
Dedang Feng, Hao Zhang, Xianqin Qiu, Hongying Jian, Qigang Wang, Ningning Zhou, Yu Ye, Jun Lu, Huijun Yan, Kaixue Tang   +9 more
doaj   +1 more source

Field Records and Observations of Insects Associated With Cantharidin [PDF]

, 2017
This paper reports on insect species not previously associated with cantharidin, the terpenoid defense mechanism of blister beetles (Meloidae). Species from the following tau were obserYed and collected: Miridae (Hemiptera); Endomychidae, Pyrochroidae ...
Young, Daniel K
core   +2 more sources

Engineering Electron Transfer Flux between Cytochrome P450 Enzyme and P450 Reductase to Enhance Serotonin Production in Escherichia Coli

Advanced Science, EarlyView.
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu, Pengling Wei, Lirong Chen, Ling Gao, Xiaole Xia   +4 more
wiley   +1 more source

Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd12L16

Angewandte Chemie, EarlyView.
Mimicking concave morphologies found in nature, we have introduced flexible, unsymmetric, tridentate ligand (L) which undergoes coordination self‐assembly into highly organized chiral Pd6L8 or Pd12L16 cages that can undergo interspecific transformations. The cages, being based on natural amphiphilic transport molecules, mediate high cellular uptake and
Subhasis Chattopadhyay, Robin Durník, Anniina Kiesilä, Elina Kalenius, Juha M. Linnanto, Pavel Babica, Jan Kuta, Radek Marek, Ondřej Jurček   +8 more
wiley   +2 more sources

Terpenoids From Cannabis Do Not Mediate an Entourage Effect by Acting at Cannabinoid Receptors

Frontiers in Pharmacology, 2020
The entourage effect was a proposed explanation for biological observations that endocannabinoid ligand activities can be modified by other lipids released from cells at the same time.
David B. Finlay, Kathleen J. Sircombe, Mhairi Nimick, Callum Jones, Michelle Glass   +4 more
doaj   +1 more source

Accounting for ALA Natural Mutations Enhances the Efficiency of Graphene Oxide Nanopriming in Bar‐Modified Arabidopsis

Advanced Science, EarlyView.
Nanopriming enhances plant resilience to environmental challenges; however, its effectiveness across diverse genetic backgrounds, including genetic modifications and natural variations, remains uncertain. These findings demonstrate that nanopriming improves efficacy when natural genetic variations are considered, particularly in genetically modified ...
Yining Wu, Rui Sun, Yueting Cui, Jun Qiao, Chengdong Zhang   +4 more
wiley   +1 more source

Terpenoid-Induced Feeding Deterrence and Antennal Response of Honey Bees [PDF]

, 2020
Multiple interacting stressors negatively affect the survival and productivity of managed honey bee colonies. Pesticides remain a primary concern for beekeepers, as even sublethal exposures can reduce bee immunocompetence, impair navigation, and reduce ...
Anderson, Troy D., Bernier, Ulrich R., Bloomquist, Jeffrey R., Larson, NIcholas R., O\u27Neal, Scott T.   +4 more
core   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, EarlyView.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis

Advanced Science, EarlyView.
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard, Adélie Salin, Sandy Ribes, Magali Monnoye, Gaëlle Champeil‐Potokar, Marie‐Sabelle Hjeij, Gwénaëlle Randuineau, Léa Le Gleau, Selma Ben Fradj, Catherine Philippe, Alexandre Benani, Isabelle Denis, Véronique Douard, Gaëlle Boudry   +13 more
wiley   +1 more source