This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
The river Dniester valley: a long record of late-Cenozoic fluvial evolution within the Eastern Carpathian foreland and East European Platform margin. [PDF]
Matoshko AV, Gibbard P.
europepmc +1 more source
Data‐Guided Photocatalysis: Supervised Machine Learning in Water Splitting and CO2 Conversion
This review highlights recent advances in supervised machine learning (ML) for photocatalysis, emphasizing methods to optimize photocatalyst properties and design materials for solar‐driven water splitting and CO2 reduction. Key applications, challenges, and future directions are discussed, offering a practical framework for integrating ML into the ...
Paul Rossener Regonia +1 more
wiley +1 more source
From degradation to restoration: addressing the environmental challenges in the Ethiopian highlands. [PDF]
Elias E +6 more
europepmc +1 more source
Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu +7 more
wiley +1 more source
The Role of Surface Science in Electrocatalysis. [PDF]
Fernández-Vidal J, Koper MTM.
europepmc +1 more source
Roadmap on Artificial Intelligence‐Augmented Additive Manufacturing
This Roadmap outlines the transformative role of artificial intelligence‐augmented additive manufacturing, highlighting advances in design, monitoring, and product development. By integrating tools such as generative design, computer vision, digital twins, and closed‐loop control, it presents pathways toward smart, scalable, and autonomous additive ...
Ali Zolfagharian +37 more
wiley +1 more source
BMPCQA: Bioinspired Metaverse Point Cloud Quality Assessment Based on Large Multimodal Models
This study presents a bioinspired metaverse point cloud quality assessment metric, which simulates the human visual evaluation process to perform the point cloud quality assessment task. It first extracts rendering projection video features, normal image features, and point cloud patch features, which are then fed into a large multimodal model to ...
Huiyu Duan +7 more
wiley +1 more source
10,000 years of centennially-resolved climate and sea-level change archived in Svalbard beach-ridge system. [PDF]
Strzelecki MC +5 more
europepmc +1 more source
Pancake Lenses through Curved Lamination for Compact Virtual Reality
This article presents an ultrathin VR optical system based on a 1.35 in. microdisplay, leveraging curved lamination technology. Compared to mainstream solutions, the proposed design demonstrates superior compactness (volume compression by 12%) and enhanced optical performance.
Jiaping Sun +5 more
wiley +1 more source

