Results 31 to 40 of about 1,084 (164)

First‐in‐human phase 1 study of KHK2455 monotherapy and in combination with mogamulizumab in patients with advanced solid tumors

Cancer, Volume 131, Issue 13, 1 July 2025.
Abstract Background Indoleamine 2,3‐dioxygenase 1 (IDO1) is a heme‐containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long‐acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme.
Timothy A. Yap, Olivier Rixe, Capucine Baldini, Ursa Brown‐Glaberman, Sergey Efuni, David S. Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H. Shiue, Yi Liu, Matthew W. Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam   +16 more
wiley   +1 more source

Ground deformation and source geometry of the 24 August 2016 Amatrice earthquake (Central Italy) investigated through analytical and numerical modeling of DInSAR measurements and structural‐geological data

Geophysical Research Letters, Volume 43, Issue 24, Page 12,389-12,398, 28 December 2016., 2016
Abstract We investigate the ground deformation and source geometry of the 2016 Amatrice earthquake (Central Italy) by exploiting ALOS2 and Sentinel‐1 coseismic differential interferometric synthetic aperture radar (DInSAR) measurements. They reveal two NNW‐SSE striking surface deformation lobes, which could be the effect of two distinct faults or the ...
G. Lavecchia, R. Castaldo, R. de Nardis, V. De Novellis, F. Ferrarini, S. Pepe, F. Brozzetti, G. Solaro, D. Cirillo, M. Bonano, P. Boncio, F. Casu, C. De Luca, R. Lanari, M. Manunta, M. Manzo, A. Pepe, I. Zinno, P. Tizzani   +18 more
wiley   +1 more source

Building resilient social protection: Lessons from Türkiye's earthquake response

International Social Security Review, Volume 78, Issue 2-3, Page 97-122, April-September 2025.
Abstract This article assesses the functioning and disaster response capacity of the Turkish social security system in the aftermath of the Kahramanmaraş‐centred earthquake that struck southeastern Türkiye on 6 February 2023, affecting 11 provinces. Türkiye's social security infrastructure, which was restructured after the 1999 Marmara earthquake, has ...
Oğuz Karadeniz
wiley   +1 more source

Seismic risk in the State of Colima, México: Application of a Simplified Methodology of the Seismic Risk Evaluation for the Localities with Low-Rise, Non-Engineered Housing

Geofísica Internacional, 2022
El estudio de riesgo sísmico es un elemento importante en la evaluación de peligros naturales, especialmente en las regiones de alta actividad sísmica y baja calidad structural de las viviendas.
Vyacheslav M. Zobin, Imelda Plascencia
doaj   +1 more source

Authoritarianism and the Emergence of Parallel State Dynamics: Evidence From the Syrian Earthquake

Digest of Middle East Studies, Volume 34, Issue 1, Winter 2025.
ABSTRACT This article investigates the Syrian regime's strategic manipulation of the February 2023 earthquake to reaffirm its authority and maintain legitimacy. The regime's response to the disaster is analyzed to understand how authoritarian states leverage natural disasters for political gains. It argues that the Assad regime's survival is not merely
Rahaf Aldoughli
wiley   +1 more source

Red semántica de terremoto y maremoto en personas expuestas directa y vicariamente Rede semântica de terremoto e tsunami em pessoas expostas diretamente e vicariamente Semantic networks of earthquake and tsunami in people exposed directly and vicariously

Psicologia em Estudo, 2012
Se busca identificar el significado de los conceptos 'terremoto' y 'maremoto' en dos grupos diferentemente expuestos al evento acaecido en Chile el 27/02/2010, en una muestra no probabilística intencional, compuesta por 240 personas provenientes de las ...
Emilio Moyano Díaz, Katerinne Muñoz Tapia, Claudia Estrada, Marcelo Leiva-Bianchi   +3 more
doaj  

El papel del medio y las emociones en la comunicación en crisis. Estudio experimental de Twitter, Facebook y ELCOMERCIO.com en Ecuador / The role of media and emotions in crisis communication: Experimental study about Twitter, Facebook and ELCOMERCIO.com

Revista Internacional de Relaciones Públicas, 2018
En la presente investigación, se toma el terremoto de Manabí (Ecuador) de 2016 como caso de estudio, a partir de la crisis asociada a la pérdida del servicio de telecomunicaciones de la empresa Movistar®. Con este propósito, se desarrolló un experimento
Patricia Henríquez-Coronel, Daniel Barredo-Ibáñez, Juan Pablo Trámpuz   +2 more
doaj   +1 more source

Vision‐Based Monitoring of Absolute and Relative Displacements in Multistory Buildings During Full‐Scale Shake‐Table Tests

Structural Control and Health Monitoring, Volume 2025, Issue 1, 2025.
Displacements are among the most important engineering response parameters to be monitored during shake‐table testing, with experiments playing a key role in studying the seismic behavior of structures. However, their accurate measurement is not a trivial task when using contact sensors.
Laura Gioiella, Fabio Micozzi, Morgan McBain, Michele Morici, Alessandro Zona, Andrea Dall’Asta, Barbara G. Simpson, Andre R. Barbosa, Jian Zhang   +8 more
wiley   +1 more source

Urbanoticias

Urbano, 2010
El terremoto y tsunami del 27 de febrero de 2010 • Generalidades. • El terremoto. • El tsunami. • Réplicas. • Víctimas y daños materiales. • Situación de seguridad pública. • Servicios básicos. • Campañas solidarias.
Alfredo Palacios Barra
doaj  

Sediment Corrections for Distributed Acoustic Sensing

Journal of Geophysical Research: Solid Earth, Volume 129, Issue 10, October 2024.
Abstract On continental margins, sediments cause significant and spatially variable delays in seismic phase arrival times. The strong impedance contrast of the sediment‐bedrock interface causes P‐wave splitting that is clearly seen on distributed acoustic sensing recordings of earthquakes, resulting in additional phase arrivals that must be picked ...
Alister Trabattoni, Clara Vernet, Martijn van den Ende, Marie Baillet, Bertrand Potin, Diane Rivet   +5 more
wiley   +1 more source