Results 121 to 130 of about 12,489 (231)

Improved Messenger RNA Stability and Biocompatibility Through Self‐Gelatinizable Nucleic Acids

Biotechnology and Bioengineering, Volume 123, Issue 4, Page 1077-1086, April 2026.
ABSTRACT Recent advances in the chemical synthesis and modification of messenger RNA (mRNA) have generated growing interest in mRNA‐based therapeutics. However, the inherent instability of mRNA in vivo and during storage remains a major challenge, requiring the development of safe and effective delivery systems.
Takumi Tanifuji, Kosuke Kusamori, Chihiro Tanaka, Hideki Sakai, Shoko Itakura, Makiya Nishikawa   +5 more
wiley   +1 more source

Transposable elements may enhance antiviral resistance in HIV-1 elite controllers

Genome Biology
Background Less than 0.5% of people living with HIV-1 are elite controllers (ECs)—individuals who maintain undetectable plasma viremia without antiretroviral therapy, despite having replication-competent viral reservoirs.
Manvendra Singh, Sabrina M. Leddy, Luis Pedro Iñiguez, Matthew L. Bendall, Douglas F. Nixon, Cédric Feschotte   +5 more
doaj   +1 more source

Endoscopic Management of Complex Duodenal Ulcer Bleeding Using Over‐the‐Scope Clips: Clinical Insights From a Regional Core Hospital

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Over‐the‐scope clips (OTSCs) are considered an effective endoscopic tool for managing upper gastrointestinal bleeding, including duodenal ulcers, mostly based on data from high‐volume centers with expert endoscopists. This study aimed to evaluate the clinical safety of OTSCs in regional hospital backgrounds and identify the factors ...
Akihiro Maruyama, Hirotaka Takeshima, Hiroshi Nakayabu, Hiroki Kato, Shintaro Tominaga, Makoto Kobayashi   +5 more
wiley   +1 more source

Pengaruh Rational Emotive Behaviour Therapy (REBT) Terhadap Afiliasi Diri pada Mahasiswa

Gadjah Mada Journal of Professional Psychology
Penelitian ini bertujuan untuk mengetahui pengaruh Rational Emotive Behaviour Therapy (REBT) terhadap afiliasi diri pada mahasiswa. Partisipan 7 orang dengan afiliasi diri rendah-sedang (N=7).
Ainurizan Ridho Rahmatulloh
doaj   +1 more source

Endoscopic Hemostasis for Gastrointestinal Stromal Tumor Hemorrhage: A Case Series and Retrospective Analysis of Risk Factors

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives Gastrointestinal stromal tumors (GISTs) are vascular tumors that can cause significant gastrointestinal hemorrhage. While endoscopic treatment is common for other hemorrhagic disorders, its role in GIST‐related hemorrhage remains unclear.
Karen Kimura, Chikamasa Ichita, Chihiro Sumida, Takashi Nishino, Miki Nagayama, Akiko Sasaki   +5 more
wiley   +1 more source

Comparison of the Usefulness of Covered and Uncovered Laser‐cut Metal Stents

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Objectives This study aimed to evaluate the clinical characteristics of laser‐cut self‐expandable metal stents (SEMS) and to compare the outcomes between covered and uncovered laser‐cut SEMS for malignant distal biliary obstruction (MDBO). Methods A multicenter retrospective analysis was conducted across eight Japanese university hospitals ...
Toshio Fujisawa, Masao Toki, Kei Saito, Yuta Hasegawa, Eisuke Iwasaki, Michihiro Saito, Katsuya Kitamura, Ryosuke Tonozuka, Takao Itoi, Ken Ito, Keiko Kaneko, Naminatsu Takahara, Tadakazu Hisamatsu, Hiroyuki Isayama   +13 more
wiley   +1 more source

Prevalence and Risk Factors of Thromboembolic Events in Dermatomyositis in China: A 10-Year Retrospective Analysis

Journal of Inflammation Research
Liubing Li,1,* Tangdan Ding,1,2,* Qiong Shi,1,* Hongji Zhu,1,2 Qinghua Ma,1,2 Mianjing Zhou,3 Ying Yuan,4 Zhihua Wen,5 Hongxu Xu,1,2 Hongxia Tan,1 Dubo Chen1 1Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-Sen ...
Li L, Ding T, Shi Q, Zhu H, Ma Q, Zhou M, Yuan Y, Wen Z, Xu H, Tan H, Chen D   +10 more
doaj  

Validation of Transcranial Electrical Stimulation (TES) Finite Element Modeling Against MREIT Current Density Imaging in Human Subjects [PDF]

, 2017
: Transcranial electrical stimulation (tES) is a non-invasive brain stimulation therapy that has shown potential in improving motor, physiological and cognitive functions in healthy and diseased population.

core  

Delayed Biliary Hemorrhage due to Pseudoaneurysm Rupture Caused by Migration of Placed Plastic Stent After Endoscopic Ultrasound‐Guided Hepaticogastrostomy

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is an effective method for cases where transpapillary approaches to pancreato‐biliary diseases are challenging, though serious complications often occur. Here, we report an extremely rare case of delayed biliary hemorrhage due to pseudoaneurysm rupture after EUS‐HGS, caused by ...
Yu Akazawa, Masahiro Ohtani, Yosuke Murata, Takuto Nosaka, Tomoko Tanaka, Kazuto Takahashi, Tatsushi Naito, Yasunari Nakamoto   +7 more
wiley   +1 more source

Rectal Arteriovenous Malformation Mimicking a Submucosal Tumor: Successful Long‐Term Outcome After Transcatheter Arterial Embolization With N‐Butyl‐2‐Cyanoacrylate‐Lipiodol

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Rectal arteriovenous malformations (AVMs) are rare vascular anomalies that pose diagnostic challenges because they may resemble submucosal tumor–like lesions. A 54‐year‐old man presented with recurrent hematochezia, and a colonoscopy revealed a protruding lesion near the dentate line.
Hiroshi Baba, Masakazu Hirakawa, Takeshi Oda, Hiromu Hidaka, Masayuki Hirata, Sho Kakinouchi, Yasuko Tamaru, Yuji Abe, Yoshiki Asayama   +8 more
wiley   +1 more source