Results 131 to 140 of about 12,489 (231)

Causal Effects of Renin–Angiotensin–Aldosterone System Inhibition on Renal Function in Patients With Chronic Kidney Disease: A Quasi‐Experimental Study

open access: yesClinical and Translational Science, Volume 19, Issue 4, April 2026.
ABSTRACT Renin–angiotensin–aldosterone system inhibitors are widely prescribed for chronic kidney disease, but their causal effect on kidney function remains uncertain. This study investigated the impact of starting renin–angiotensin blockade on renal function in adults with kidney disease.
Tae Ryom Oh   +4 more
wiley   +1 more source

Difference in Pain and Discomfort of Comparable Wrist Movements Induced by Magnetic or Electrical Stimulation for Peripheral Nerves in the Dorsal Forearm

open access: yesMedical Devices: Evidence and Research, 2020
Genji Abe,1,2,* Hideki Oyama,3,* Zhenyi Liao,1 Keita Honda,1 Kenji Yashima,4 Akihiko Asao,5 Shin-Ichi Izumi1,3 1Department of Physical Medicine and Rehabilitation, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan; 2Department of ...
Abe G   +6 more
doaj  

Variation in Microbiome Composition and Faecal Metabolites Are Associated With Differential Susceptibility to DSS‐Induced Colitis

open access: yesImmunology, Volume 177, Issue 4, Page 766-783, April 2026.
C57BL/6 mice from Charles River Laboratories (CR) have enhanced mucosal immune action relative to C57BL/6 mice from Jackson Laboratories (JAX). CR mice are more susceptible to severe DSS‐induced colitis than JAX mice. Co‐housing transfers colitis susceptibility from CR mice to JAX mice.
Jessica M. Till   +8 more
wiley   +1 more source

Feasibility study of in‐house second‐channel calibration of dual‐channel electrometers using a battery‐powered current source

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Background An ionization chamber and electrometer allow measurement of the absorbed dose to water. A sensitivity comparison between electrometers is essential for quality control, and an efficient method is available to accurately measure the electrometer sensitivity coefficient without using a linear accelerator (linac).
Hayato Tsuno   +7 more
wiley   +1 more source

Potencial efecto hipotensor de esteroides sexuales masculinos [PDF]

open access: yes, 2019
Tesis doctoral inédita cotutelada por Universidad Nacional Autónoma de México y la Universidad Autónoma de Madrid, Facultad de Medicina, Departamento de Bioquímica.
Isidoro García, Lucía
core  

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 9, 6 March 2026.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche   +8 more
wiley   +1 more source

Targeting the Causes of Intractable Chronic Constipation in Children: The Nuclear Transit Study (NTS) [PDF]

open access: yes, 2011
Bridget R. Southwell   +8 more
core   +2 more sources

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

open access: yesAdvanced Science, Volume 13, Issue 17, 23 March 2026.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu   +15 more
wiley   +1 more source

Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
Schematic illustration of mTEM8‐loaded cationic liposome (cLipo‐Man/mTEM8) therapeutics for improved triple‐negative breast cancer immunotherapy. Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy.
Kexin Deng   +10 more
wiley   +1 more source

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