Results 101 to 110 of about 2,879 (174)

Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond [PDF]

open access: yes, 2014
The development and application of diverse BAC transgenic rodent lines has enabled rapid progress for precise molecular targeting of genetically-defined cell types in the mammalian central nervous system. These transgenic tools have played a central role
Guoping Feng, Jonathan T. Ting
core   +1 more source

A Piglet with Concurrent Polioencephalomyelitis due to Porcine Teschovirus and Postweaning Multisystemic Wasting Syndrome

open access: yesJournal of Veterinary Medical Science, 2008
A piglet developed respiratory distress followed by difficulty in standing and unsteady gait. The lesions were characterized by polioencephalomyelitis with the predominant distribution in the brain stem, as well as lymphocyte depletion and histiocyte infiltration with cytoplasmic inclusion bodies in the lymphoid tissues throughout the body and ...
Maki, Takahashi   +3 more
openaire   +3 more sources

Prevalence and Genetic Diversity of Human Enteroviruses in the Context of Poliovirus Eradication [PDF]

open access: yes, 2012
Viruses belonging to the family Picornaviridae are small, non-enveloped viruses with a single-stranded, positive-sense RNA genome. Up to present, thirteen genera within this large family have been designated by the International Committee on Taxonomy of ...
Sanden, S.M.G. (Sabine) van der
core  

Neuropeptide VF neurons promote sleep via the serotonergic raphe [PDF]

open access: yes, 2020
Although several sleep-regulating neuronal populations have been identified, little is known about how they interact with each other to control sleep/wake states.
Andreev, Andrey   +6 more
core  

Binary recombinase systems for high-resolution conditional mutagenesis [PDF]

open access: yes, 2017
Conditional mutagenesis using Cre recombinase expressed from tissue specific promoters facilitates analyses of gene function and cell lineage tracing. Here, we describe two novel dual-promoter-driven conditional mutagenesis systems designed for greater ...
Hermann, Mario   +9 more
core  

PLoS Negl Trop Dis [PDF]

open access: yes
Sosuga virus (SOSV) is a recently discovered zoonotic paramyxovirus isolated from a single human case in 2012; it has been ecologically and epidemiologically associated with transmission by the Egyptian rousette bat (Rousettus aegyptiacus).

core  

Engineering recombinant replication-competent bluetongue viruses expressing reporter genes for in vitro and non-invasive in vivo studies

open access: yesMicrobiology Spectrum
Bluetongue virus (BTV) is the causative agent of the important livestock disease bluetongue (BT), which is transmitted via Culicoides bites. BT causes severe economic losses associated with its considerable impact on health and trade of animals.
Sergio Utrilla-Trigo   +9 more
doaj   +1 more source

A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion. [PDF]

open access: yes, 2019
Field cancerization is a premalignant process marked by clones of oncogenic mutations spreading through the epithelium. The timescales of intestinal field cancerization can be variable and the mechanisms driving the rapid spread of oncogenic clones are ...
Agarwal, Pankaj   +16 more
core   +1 more source

A stem-cell-derived platform enables complete Cryptosporidium development in vitro and genetic tractability [PDF]

open access: yes, 2019
Despite being a frequent cause of severe diarrheal disease in infants and an opportunistic infection in immunocompromised patients, Cryptosporidium research has lagged due to a lack of facile experimental methods.
Baldridge, Megan T   +13 more
core   +1 more source

Teschovirus Encephalomyelitis in Pigs and Serological Survey of Porcine Teschovirus and Porcine Enterovirus B in Saga Prefecture

open access: yesJournal of the Japan Veterinary Medical Association, 2012
Daisuke NISHI   +3 more
openaire   +2 more sources

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