Results 141 to 150 of about 17,805,684 (388)

Mismatch Repair System Genomic Scars in Gastroesophageal Cancers: Biology and Clinical Testing [PDF]

open access: gold, 2020
Gianluca Lopez   +3 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Identification of the Glyceraldehyde-3-Phosphate Dehydrogenase (GeGAPDH) Gene Family in Gastrodia elata Revealing Its Response Characteristics to Low-Temperature and Pathogen Stress

open access: yesPlants
The glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene plays a pivotal role in the glycolysis/gluconeogenesis process, contributing significantly to glycosyl donor synthesis, plant growth and development, and stress responses.
Yaxing Yan   +4 more
doaj   +1 more source

Pengembangan Media Pembelajaran Pembelahan Sel Dengan Menggunakan Macromedia Flash Untuk Kelas XII SMA [PDF]

open access: yes, 2014
This research was conducted to developing Biology media-learning by employing macromedia flash in studying cell division for X grade high school students based on the result of validation by the expert team and the students responses.
Lestari, R. (Rena)
core  

Diagnosing students' biology misconceptions using an android-based four-tier multiple choice test [PDF]

open access: hybrid, 2023
Nukhbatul Bidayati Haka   +4 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

PENGARUH MODEL PEMBELAJARAN GROUP INVESTIGATION TERHADAP HASIL BELAJAR BIOLOGI DITINJAU DARI TINGKAT KREATIVITAS SISWA KELAS X SMAN 2 KARANGANYAR [PDF]

open access: yes, 2012
This research aimed to know, (1) The existence of significant influence’s Group Investigation model towards the results study of Biology class X SMAN 2 Karanganyar, (2) The existence of significant influence’s creativity level towards the results study ...
B, Aulia Richvana   +2 more
core   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

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