Results 161 to 170 of about 15,644,828 (310)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Clindamycin-resistant among Staphylococcus aureus: Investigation into phenotypic and genotypic profiles. [PDF]

PLoS One
Khursheed M, Sulaiman M, Alhassan AM, Al Awad TH, Ibrahim AE, Wilson G, Abdelrahaman HA, Eltai NO.   +7 more
europepmc   +1 more source

The Rodent Forced Swim Test Measures Stress-Coping Strategy, Not Depression-like Behavior.

ACS Chemical Neuroscience, 2017
K. Commons, Aram B. Cholanians, J. A. Babb, D. G. Ehlinger   +3 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Alternative to the statistical mass confusion of testing for "no effect". [PDF]

J Cell Biol
Morgan JL.
europepmc   +1 more source

Practicum Learning Techniques in Brassica chinensis Pesticide Contamination Test on UISU FKIP Biology Students 2018-2019

, 2019
Yusri Fefiani
openalex   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Independent assessment of a point of care HCV RNA test by laboratory analytical testing and a prospective field study in the U.S. [PDF]

PLoS One
Miller LS, Rao A, Tunnell K, Wang YF, Parsons R, McLendon K, Bassit L, Patel M, Bowers HB, Sabino C, Ramachandra T, Saeed F, Schinazi RF, Lam W, Sullivan JA, Fluker SA.   +15 more
europepmc   +1 more source

Construction and test of an efficient biophotonic imaging (BPI) reporter system to study pneumococcal biology in vitro and in vivo

, 2019
Nada Alkhorayef
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source