Results 161 to 170 of about 3,366,505 (350)

Integrative transcriptomic analysis identifies emetine as a promising candidate for overcoming acquired resistance to ALK inhibitors in lung cancer

Molecular Oncology, EarlyView.
We propose an efficient strategy to suppress ALK inhibitor (ALKi) resistance. By analyzing transcriptome data, we identified emetine as a potential inhibitor. We demonstrated that emetine exhibited effectiveness in inhibiting the growth of ALKi‐resistant cells, and further interpreted its impact on the resistant signatures through drug‐induced RNA ...
Sang‐Min Park, Keeok Haam, Haejeong Heo, Doyeong Kim, Min‐Ju Kim, Hyo‐Jung Jung, Seongwon Cha, Mirang Kim, Haeseung Lee   +8 more
wiley   +1 more source

Large Language Models in Plant Biology [PDF]

arXiv
Large Language Models (LLMs), such as ChatGPT, have taken the world by storm and have passed certain forms of the Turing test. However, LLMs are not limited to human language and analyze sequential data, such as DNA, protein, and gene expression.
arxiv  

Enhancement of Students\u27 Biological Literacy and Critical Thinking of Biology Through Socio-Biological Case-Based Learning [PDF]

, 2017
Biology is a leading science and a foundation in everyday life for all people. Biology student teachers need to be equipped with biological literacy and critical thinking skills in order to teach biology in the future.
Pratiwi, H. E. (H), Susanto, H. (H), Susilo, H. (H), Suwono, H. (H)   +3 more
core  

Biology and the Gender Gap in Educational Performance: The Role of Prenatal Testosterone in Test Scores [PDF]

, 2018
Anne C. Gielen, Esmée Zwiers
openalex   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Evaluation protocols for the extraction of genomic DNA from Bovine blood

Journal of the Selva Andina Research Society, 2016
Basic studies on DNA extraction techniques are very important for the success of scientific papers in the field of molecular biology. The extraction and purification of nucleic acids are critical steps for establishing further genetic analysis.
Crispim Bruno do Amaral, Nascimento André Vieira, Romero Ândrea Renata da Silva, Fernandes Juliana dos Santos, Banari Alexandre Campos, Seno Leonardo de Oliveira, Grisolia Alexéia Barufatti   +6 more
doaj  

Prognostic significance of pulmonary function tests in dyskeratosis congenita, a telomere biology disorder [PDF]

, 2019
Neelam Giri, Sandhiya Ravichandran, Youjin Wang, Shahinaz M. Gadalla, Blanche P. Alter, Joseph R. Fontana, Sharon A. Savage   +6 more
openalex   +1 more source

Genomic landscape and preclinical models of angiosarcoma

Molecular Oncology, EarlyView.
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton, Bozhi Liu, Lauren E. Gartenhaus, Jason A. Hanna   +3 more
wiley   +1 more source

Origin traceability and adulteration detection of soybean using near infrared hyperspectral imaging

Food Frontiers
Stable isotopes, multi‐elements, metabolic profiles, and integrated spectroscopic fingerprints are priority options for food geographical origin traceability. However, til now, it is still hard to detect adteration with the same one from other geographic
Xue Li, Du Wang, Li Yu, Fei Ma, Xuefang Wang, Dolores Pérez‐Marín, Peiwu Li, Liangxiao Zhang   +7 more
doaj   +1 more source

A Test of the Thermodynamics of Evolution [PDF]

arXiv
Recent research has extended methods from the fields of thermodynamics and statistical mechanics into other disciplines. Most notably, one recent work creates a unified theoretical framework to understand evolutionary biology, machine learning, and thermodynamics. We present simulations of biological evolution used to test this framework.
arxiv