Results 181 to 190 of about 17,805,684 (388)

The long winter model of Martian biology: A speculation [PDF]

open access: yes
An estimated mean thickness of about 1 km of frost in the Martian north polar cap summer remnant, if vaporized, would yield about 1000 g/sq cm of atmosphere over the planet, higher global temperatures through the greenhouse effect, and a greatly ...
Sagan, C.
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Synthetic DNA Synthesis and Assembly: Putting the Synthetic in Synthetic Biology.

open access: yesCold Spring Harbor Perspectives in Biology, 2017
R. Hughes, A. Ellington
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Evaluation protocols for the extraction of genomic DNA from Bovine blood

open access: yesJournal of the Selva Andina Research Society, 2016
Basic studies on DNA extraction techniques are very important for the success of scientific papers in the field of molecular biology. The extraction and purification of nucleic acids are critical steps for establishing further genetic analysis.
Crispim Bruno do Amaral   +6 more
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Can State Language Policies Distort Students' Demand for Higher Education? [PDF]

open access: yes
This paper takes advantage of a recent policy experiment in Ukraine's secondary education system to study the effect of stricter requirements for proficiency in the state language on linguistic minority students’ demand for, as well as opportunities to ...
Muravyev, Alexander, Talavera, Oleksandr
core  

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