Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Between experience and measurement: masters athletes’ perceptions of the 5Cs and a proposed measure
Frontiers in Sports and Active LivingIntroductionThis study aimed to evaluate Masters athletes’ perceptions of the Cs of Positive Youth Development (competence, confidence, connection, care, character, contribution, and risk behavior) and to develop a measure to assess these dimensions in ...
Maynara Priscila Pereira da Silva +1 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Leadership for Educational Inclusion: Design and Validation of a Measurement Instrument
Education SciencesThis article addresses the validation of an instrument designed to measure organizational leadership practices for inclusion and evaluates the said instrument’s factorial structure and convergent validity.
Daniela Zúñiga +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Multi-outcome construction policies : comparative analysis of western australian and queensland policies [PDF]
, 2009 This document provides an overview of the differences and similarities in the objectives and implementation frameworks of the training and employment policies applying to public construction projects in Western Australia and Queensland.
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A construção de uma escala de estratégias de aprendizagem para alunos do ensino fundamental
Psicologia: Teoria e PesquisaEmbora as estratégias de aprendizagem sejam importantes para o processo de escolarização, existe uma carência de instrumentos nacionais que possibilitem um conhecimento do repertório referente a elas em estudantes brasileiros.
Evely Boruchovitch +6 more
doaj +1 more source