Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Uncertainty Analysis of a Multi-Sensor Fusion Measurement Chain for Blade Collision Warning in Coaxial Twin-Rotor Helicopters. [PDF]
Zheng W +5 more
europepmc +1 more source
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Construction of a radiomics-based diagnostic nomogram for patellofemoral osteoarthritis-using lateral knee X-ray images from a South China population. [PDF]
Guo X +6 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Risk and contract management practices, and construction projects performance: A test of moderation by managerial skills. [PDF]
Karugu WH, Mburugu KN, Njeru DM.
europepmc +1 more source
Research on the Performance Prediction of Fly Ash Slurry by Neural Network Based on Information Bottleneck Theory and Attention Mechanism. [PDF]
Deng B +6 more
europepmc +1 more source
Apparent diffusion coefficient-based single-sequence radiomics integrated with clinical variables and Prostate Imaging Reporting and Data System for predicting clinically significant prostate cancer. [PDF]
Huang J, Wan Y, Wang J, Liu Q, Li H.
europepmc +1 more source
A two-stage algebraic framework for designing cryptographically strong S-boxes for secure image encryption. [PDF]
Razzaque A +3 more
europepmc +1 more source
A Knowledge-Enhanced Iterative Reasoning Framework for Accurate and Traceable Fault Diagnosis in Distributed Service Systems. [PDF]
Zhang Y, Zhang J, Wang J, Zhang S.
europepmc +1 more source

