Results 81 to 90 of about 10,239,739 (303)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Construction and validation of Multifaceted Inventory for the Self-Report of Psychopathy (MISP) [PDF]
The aim of this study was to construct, evaluate psychometrically and validate the Multifaceted Inventory for the Self-Report of Psychopathy (MISP). The pilot version consisted of 100 items arranged in 10 indicators related to affective, behavioral and ...
Cupać Đorđe +4 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Methodology of Assessment of Athletes' Jumping Skills Using Electronic Equipment
Background and Study. Vertical jump performance is a critical factor in volleyball, significantly influencing actions like spiking, blocking, and serving.
Soyib Tajibaev +5 more
doaj +1 more source
Relata-se a construção de um instrumento para avaliar o ajustamento de estudantes nos ambientes familiar, escolar e social, aplicado coletivamente em 440 alunos do ensino fundamental.
Fermino Fernandes Sisto, Lílian Pacheco
doaj +1 more source
Final report : task 4 : waste minimisation in construction [PDF]
The Regenerating Construction Project for the CRC for Construction Innovation aims to\ud assist in the delivery of demonstrably superior ‘green’ buildings.
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
A Hierachical Infrastrucutre for SOC Test Management [PDF]
HD2BIST - a complete hierarchical framework for BIST scheduling, data-patterns delivery, and diagnosis of complex systems - maximizes and simplifies the reuse of built-in test architectures.
Zorian Y. +4 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source

