Results 121 to 130 of about 23,145 (245)

Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model

open access: yesAdvanced Science, EarlyView.
Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo   +16 more
wiley   +1 more source

A General and Modular Approach to Solid-State Integration of Zero-Dimensional Quantum Systems. [PDF]

open access: yesNano Lett
Kavand M   +15 more
europepmc   +1 more source

Electrochemiluminescence Drives Photodynamic Therapy In Vivo

open access: yesAdvanced Science, EarlyView.
Electrochemiluminescence (ECL)‐driven photodynamic therapy (PDT) for in vivo cancer treatment is reported for the first time. The flexible ECL patch exhibits stable and intense luminance under alternating current voltage, enabling efficient photosensitization to generate reactive oxygen species that damage cancer cells, thus leading to significant ...
Jia‐Bao Lin   +5 more
wiley   +1 more source

Spatial mapping of influenza and coronavirus receptors in the respiratory and intestinal tract epithelium of beef cattle using advanced PixF image analysis. [PDF]

open access: yesSci Rep
Twu NC   +9 more
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Characterizing dynamics of PRRSV RNA positivity over time in sows after live virus exposure and associated risk factors based on TOSc samples. [PDF]

open access: yesBMC Vet Res
Li P   +15 more
europepmc   +1 more source

Transient Antiskyrmion‐Mediated Topological Transitions in Isotropic Magnets

open access: yesAdvanced Science, EarlyView.
A transient antiskyrmion‐mediated pathway that drives repeated stripe‐to‐skyrmion transitions is revealed, producing a net increase in topological charge in isotropic Dzyaloshinskii–Moriya interaction films. Experiments and simulations identify the antiskyrmion as a metastable excitation, enabling stochastic bitstream generation for probabilistic ...
Bingqian Dai   +18 more
wiley   +1 more source

Studies of <i>Piper auritum</i> Kuntz's Mutagenic and Antimutagenic Properties Using the Ames Test. [PDF]

open access: yesMetabolites
Muñoz-Carrillo LS   +6 more
europepmc   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

open access: yesAdvanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao   +19 more
wiley   +1 more source

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