Results 51 to 60 of about 14,106,922 (303)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Automatic Test Environment of Speech Recognition Software for Intelligent Display
Kongzhi Yu Xinxi Jishu, 2020 Software test of smart display speech recognition software involves a combination of multiple external environmental noise, speed of speech, and intonation of instruction voice, which causes a large number of test case combinations and high execution ...
ZHONG Li, LIU Buqi, YANG Ying
doaj
Test prioritization in continuous integration environments [PDF]
Journal of Systems and Software, 2018 Journal of Systems and Software (2018)
Oivo Markku +3 more
openaire +4 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Journal of Marine Science and Engineering, 2020 Global warming is becoming worse owing to carbon dioxide emissions around the world, and eco-friendly energy for reducing carbon dioxide emissions is gaining importance. Wind power plants are the most representative of the environmentally friendly energy
Su-Won Son, Jong-Chan Yoon, Jin-Man Kim
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Research on BHAST Test Method for Plastic Encapsulated Microcircuit
IEEE AccessCompared to metal packaging and ceramic packaging, plastic encapsulated microcircuits (PEMs) have the advantages of light weight and low cost. However, due to their non-airtightness, they are prone to delamination, corrosion, and other failures in humid ...
Yuege Zhou +6 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source