Results 71 to 80 of about 187,525 (244)

Node-balancing by edge-increments [PDF]

open access: yes, 2015
Suppose you are given a graph $G=(V,E)$ with a weight assignment $w:V\rightarrow\mathbb{Z}$ and that your objective is to modify $w$ using legal steps such that all vertices will have the same weight, where in each legal step you are allowed to choose an
A. Schrijver   +12 more
core   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease [PDF]

open access: yes, 2016
BACKGROUND: Impaired olfaction is an important feature in Parkinson's disease (PD) and other neurological diseases. A variety of smell identification tests exist such as "Sniffin' Sticks" and the University of Pennsylvania Smell Identification Test ...
Baig, F   +17 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Symbolic Software for the Painleve Test of Nonlinear Ordinary and Partial Differential Equations

open access: yes, 2006
The automation of the traditional Painleve test in Mathematica is discussed. The package PainleveTest.m allows for the testing of polynomial systems of ordinary and partial differential equations which may be parameterized by arbitrary functions (or ...
Ablowitz M J   +32 more
core   +1 more source

Hydrodynamic reductions of multi-dimensional dispersionless PDEs: the test for integrability [PDF]

open access: yes, 2003
A (d+1)-dimensional dispersionless PDE is said to be integrable if its n-component hydrodynamic reductions are locally parametrized by (d-1)n arbitrary functions of one variable.
Ferapontov, E. V., Khusnutdinova, K. R.
core   +4 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Placing Multiple Tests on a Common Scale Using a Post-test Anchor Design: Effects of Item Position and Order on the Stability of Parameter Estimates

open access: yesFrontiers in Applied Mathematics and Statistics, 2018
When there is an interest in tracking longitudinal trends of student educational achievement using standardized tests, the most common linking approach generally involves the inclusion of a common set of items across adjacent test administrations ...
Davide Marengo   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Developing Student, Family, and School Constructs From NLTS2 Data [PDF]

open access: yes, 2015
The purpose of this study was to use data from the National Longitudinal Transition Study–2 (NLTS2) to (a) conceptually identify and empirically establish student, family, and school constructs; (b) explore the degree to which the constructs can be ...
Garnier-Villarreal, Mauricio   +1 more
core   +1 more source

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