Results 141 to 150 of about 11,258,936 (255)

Peters et al. Delusions Inventory - German version

open access: yes
Die deutsche Adaptation des PDI, PDI-G, als Kurz- (k = 21 Items) und Langfassung (k = 40 Items) erfasst auf drei Dimensionen (Besorgnis, Zeitliche Beschäftigung, Überzeugungsstärke) subklinischen Wahn bei Erwachsenen.
Lincoln, T. M.
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The Revised UCLA Loneliness Scale (Russell, D., Peplau, L. A. & Cutrona, C., 1980) - Cologne version

open access: yes
Die KSE ist eine Adaptation des amerikanischen Originals und misst mit 20 Items Einsamkeit. Reliabilität: Die interne Konsistenz nach Cronbachs Alpha und die Split-half-Reliabilität lagen bei .88, die Stabilität nach einem 3-Monatsintervall bei rtt = .72.
Lamm, H., Stephan, E., Fäth, M.
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Test Track; aerial view

open access: yes
Aerial view of the concrete tractor test track and east campus of the University of Nebraska-Lincoln looking toward the southeast.
Nebraska Tractor Test Laboratory
core  

test

open access: yes, 2015
testtesttes
test, test
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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