Results 1 to 10 of about 1,611,461 (208)

Decreased phenol sulfotransferase activities associated with hyperserotonemia in autism spectrum disorders

Translational Psychiatry, 2021
Hyperserotonemia is the most replicated biochemical abnormality associated with autism spectrum disorders (ASD). However, previous studies of serotonin synthesis, catabolism, and transport have not elucidated the mechanisms underlying this ...
Cécile Pagan, Marion Benabou, Claire Leblond, Freddy Cliquet, Alexandre Mathieu, Nathalie Lemière, Hany Goubran-Botros, Richard Delorme, Marion Leboyer, Jacques Callebert, Thomas Bourgeron, Jean-Marie Launay   +11 more
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Testosterone Increases the Emission of Ultrasonic Vocalizations With Different Acoustic Characteristics in Mice

Frontiers in Psychology, 2021
Testosterone masculinizes male sexual behavior through an organizational and activational effects. We previously reported that the emission of ultrasonic vocalizations (USVs) in male mice was dependent on the organizational effects of testosterone ...
Takefumi Kikusui, Miku Sonobe, Yuuki Yoshida, Miho Nagasawa, Elodie Ey, Fabrice de Chaumont, Thomas Bourgeron, Kensaku Nomoto, Kazutaka Mogi   +8 more
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Detecting Central Auditory Processing Disorders in Awake Mice

Brain Sciences, 2023
Mice are increasingly used as models of human-acquired neurological or neurodevelopmental conditions, such as autism, schizophrenia, and Alzheimer’s disease.
Camille Dejean, Typhaine Dupont, Elisabeth Verpy, Noémi Gonçalves, Sabrina Coqueran, Nicolas Michalski, Sylvie Pucheu, Thomas Bourgeron, Boris Gourévitch   +8 more
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Exploring the multidimensional nature of repetitive and restricted behaviors and interests (RRBI) in autism: neuroanatomical correlates and clinical implications

Molecular Autism, 2023
Background Repetitive and restricted behaviors and interests (RRBI) are core symptoms of autism with a complex entity and are commonly categorized into ‘motor-driven’ and ‘cognitively driven’.
Aline Lefebvre, Nicolas Traut, Amandine Pedoux, Anna Maruani, Anita Beggiato, Monique Elmaleh, David Germanaud, Anouck Amestoy, Myriam Ly-Le Moal, Christopher Chatham, Lorraine Murtagh, Manuel Bouvard, Marianne Alisson, Marion Leboyer, Thomas Bourgeron, Roberto Toro, Guillaume Dumas, Clara Moreau, Richard Delorme   +18 more
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Exercise and Cognitive Function [PDF]

Journal of Clinical Medicine, 2019
Cognitive function is associated with longevity and is of critical importance for optimal daily functioning [...]
Paul D. Loprinzi, Ashley Lovorn
openaire   +2 more sources

Cognitive reserve mediates the severity of certain neuropsychological deficits related to cocaine use disorder [PDF]

, 2020
Introduction: The concept of cognitive reserve (CR) is being considered in the field of substance use disorder (SUD) by observing that there are individuals whose brain alterations are not related to the cognitive symptomatology they present.
Ladrón de Guevara-Miranda, David, Pérez-Rivas, Aroa, Sampedro-Piquero, Patricia, Santin-Nuñez, Luis Javier, Vicario, Selene   +4 more
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Cortico-Cerebellar neurodynamics during social interaction in Autism Spectrum Disorders

NeuroImage: Clinical, 2023
Background: Exploring neural network dynamics during social interaction could help to identify biomarkers of Autism Spectrum Disorders (ASD). A cerebellar involvement in autism has long been suspected and recent methodological advances now enable ...
Fleur Gaudfernau, Aline Lefebvre, Denis-Alexander Engemann, Amandine Pedoux, Anna Bánki, Florence Baillin, Benjamin Landman, Anna Maruani, Frederique Amsellem, Thomas Bourgeron, Richard Delorme, Guillaume Dumas   +11 more
doaj   +1 more source

Interactive Psychometrics for Autism With the Human Dynamic Clamp: Interpersonal Synchrony From Sensorimotor to Sociocognitive Domains

Frontiers in Psychiatry, 2020
The human dynamic clamp (HDC) is a human–machine interface designed on the basis of coordination dynamics for studying realistic social interaction under controlled and reproducible conditions.
Florence Baillin, Florence Baillin, Aline Lefebvre, Aline Lefebvre, Amandine Pedoux, Yann Beauxis, Denis A. Engemann, Anna Maruani, Frédérique Amsellem, J. A. Scott Kelso, J. A. Scott Kelso, Thomas Bourgeron, Richard Delorme, Richard Delorme, Guillaume Dumas, Guillaume Dumas, Guillaume Dumas, Guillaume Dumas   +17 more
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. [PDF]

, 2020
NMDA receptors (NMDARs) play subunit-specific roles in synaptic function and are implicated in neuropsychiatric and neurodegenerative disorders. However, the in vivo consequences and therapeutic potential of pharmacologically enhancing NMDAR function via
Chan, Connie, Chen, Yelin, Deshmukh, Gauri, Elstrott, Justin, Gill, T Michael, Hackos, David H, Hanson, Jesse E, Jiang, Zhiyu, Khan, Abdullah S, Kim, Thomas A, Liederer, Bianca M, Liu, Benjamin, Ma, Keran, Palop, Jorge J, Saillet, Sandrine, Scearce-Levie, Kimberly, Schwarz, Jacob B, Sellers, Benjamin D, Sheng, Morgan, Simms, Jeffrey, Solanoy, Hilda, Volgraf, Matthew, Wang, Tzu-Ming, Weber, Martin, Weimer, Robby M, Yu, Gui-Qiu   +25 more
core   +1 more source

Induced pluripotent stem cells as a tool to study brain circuits in autism-related disorders

Stem Cell Research & Therapy, 2018
The mammalian brain is a very complex organ containing an estimated 200 billion cells in humans. Therefore, studying human brain development has become very challenging given all the data that are available from different approaches, notably genetic ...
Aline Vitrac, Isabelle Cloëz-Tayarani
doaj   +1 more source