Results 121 to 130 of about 704,956 (316)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Metamorphic Testing with Causal Graphs
2023 IEEE Conference on Software Testing, Verification and Validation (ICST), 2023 Andrew G. Clark +3 more
openaire +2 more sources
Analyzing Graph Out-of-Distribution Generalization through Representational Similarity Measures [PDF]
openThis thesis focuses on analyzing graph out-of-distribution (OOD) generalization through representational similarity measures. While the current literature utilizes representational similarity measures to assess model performance, existing analyses ...
BULAT, NIKOLA
core
A graph-search based approach to bpel4ws test generation [PDF]
, 2006 —Business Process Execution Language for Web Services (BPEL4WS) is a kind of concurrent programming languages with several special features that raise special challenges for verification and testing.
Yuan Yuan, Zhongjie Li, Wei Sun
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Recognizing Partial Cubes in Quadratic Time
Journal of Graph Algorithms and Applications, 2011 We show how to test whether a graph with n vertices and m edges is a partial cube, and if so how to find a distance-preserving embedding of the graph into a hypercube, in the near-optimal time bound O(n2), improving previous O(nm)-time solutions.
David Eppstein
doaj +1 more source
Unconstraining graph-constrained group testing
CoRR, 2018 In network tomography, one goal is to identify a small set of failed links in a network, by sending a few packets through the network and seeing which reach their destination. This problem can be seen as a variant of combinatorial group testing, which has been studied before under the moniker "graph-constrained group testing." The main contribution of ...
Spang, Bruce, Wootters, Mary
openaire +4 more sources
The induced path function, monotonicity and betweenness [PDF]
The induced path function $J(u, v)$ of a graph consists of the set of all vertices lying on the induced paths between vertices $u$ and $v$. This function is a special instance of a transit function.
Changat, M., Mathew, J., Mulder, H.M.
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source