Results 51 to 60 of about 955,170 (266)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Core Belief Scale (2nd version)

open access: yes
Die CorBel-Skala ist ein Selbsteinschätzungsinstrument zur Erfassung der 97 Nuancen des CorBel-Modells, des bisher differenziertesten Modells zu Glaubenssätzen.
Mussel, P.
core   +1 more source

Verfahrensdokumentation für NaWi-Test: Test über das Wissen im nachhaltigen Wirtschaften

open access: yes, 2019
Der NaWi-Test ist ein standardisierter Test zur Erfassung des Fachwissens über nachhaltiges Wirtschaften von Auszubildenden, Schülerinnen und Schülern, Lehrkräften sowie Beschäftigten in Unternehmen. Er umfasst 15 empirisch geprüfte Aufgaben, die jeweils
Heubischl, S.   +5 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Verfahrensdokumentation für BDT: Bicycle Drawing Test

open access: yes, 2012
Der BDT eignet sich als Screening zur Erfassung visuo-konstruktiver Leistungen im klinisch-neuropsychologischen Setting. Das Verfahren zielt darauf ab, kognitive Störungen bei Patienten mit zerebralen Schädigungen abzubilden.
Merten, T., Diederich, C.
core   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

CASQ. Coping Across Situations Questionnaire

open access: yes
Der CASQ erfasst das individuelle Bewältigungsverhalten von Jugendlichen in belastenden Situationen. 20 Bewältigungsstrategien in acht altersspezifischen Problembereichen werden den drei Subskalen "Aktive Bewältigung", "Internale Bewältigung" und ...
Seiffge-Krenke, I.
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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