Results 191 to 200 of about 60,819 (286)

Epigenetically‐Upregulated CD98 Shed Light on the Precancerous Diagnosis and Prognosis Prediction of Esophageal Cancer

Cancer Science, EarlyView.
This study confirmed that hypomethylation‐induced upregulation of CD98 promoted ESCC cell proliferation by regulating the cell cycle and was correlated with poorer overall survival of ESCC patients. Combined panels of immunohistochemistry (CD98 and P53) are recommended for accurate diagnosis of esophageal precancerous lesions.
Xue Zhang, Mengfei Sun, Na Li, Jie Yu, Wenjie Wang, Ju Yang, Hongyan Wu, Linyue Zhao, Huakun Zhang, Lan Yang, Feng Li, Qi Sun, Yunzhao Chen, Xiaobin Cui   +13 more
wiley   +1 more source

Diagnostic and prognostic role of NLR in testicular cancer. [PDF]

Explor Target Antitumor Ther
Sarejloo S, Babadi S, Khanzadeh S, Salimi A, Clark A, Khazaeli D, Khanzadeh M, Ghaedi A, Lucke-Wold B.   +8 more
europepmc   +1 more source

Sporadic testicular germ cell cancers do not exhibit specific alteration in CAG/CTG repeats containing genes expressed in human testis [PDF]

, 2001
Yasumasa Ono, Eva Rajpert De-Meyts, Georges Guellaën, Frédérique Bulle   +3 more
openalex   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Comparative analysis prediction of prostate and testicular cancer mortality using machine learning: accuracy study. [PDF]

Sao Paulo Med J
Albuquerque Neto AG, Nery DM, Braz JPA, Nascimento CFD, Oliveira TA, Barra BGA, Nobre LTDB, Bonfada D, Braz JKFDS.   +8 more
europepmc   +1 more source

Testicular Function After Immune‐Checkpoint Inhibitors Treatment

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To investigate the effects of immune‐checkpoint inhibitors (ICIs) on spermatogenesis and testicular endocrine function in reproductive‐age men with melanoma. Design Prospective, mixed longitudinal and cross‐sectional cohort study. Patients Twenty‐nine men aged 19–46 years undergoing ICI therapy for melanoma at two Australian centres ...
Andrea Boutros, Amanda Idan, Sue Sleiman, Feyrous Bacha, Ting Zhang, Veena Jayadev, Alexander M. Menzies, Georgina V. Long, David J. Handelsman   +8 more
wiley   +1 more source

Late side effects of testicular cancer and treatment: a comprehensive review. [PDF]

Discov Oncol
Khan MR, Sheehan PK, Bazin A, Leonard C, Aleem U, Corrigan L, McDermott R.   +6 more
europepmc   +1 more source

Deep Phenotyping of Pathology‐Confirmed Benign Lesions in PTEN Hamartoma Tumor Syndrome Patients

Clinical Genetics, EarlyView.
Gastrointestinal, skin, thyroid, and vascular lesions are frequently present in PTEN Hamartoma Tumor Syndrome patients with little to no difference between sexes or by index status. Early‐onset lipomas (< 20 years) may be useful for early recognition of patients, and uterine polyps should be considered for inclusion as a PHTS‐related lesion.
Ane J. Schei‐Andersen, Janneke H. M. Schuurs‐Hoeijmakers, Rachel van der Post, Arjen R. Mensenkamp, Jolanda Schieving, PTEN Study Group, Muriel A. Adank, Mirjam de Jong, Marjolijn C.J. Jongemans, Liselotte P. van Hest, Yvette van Ierland, Edward M. Leter, Maartje Nielsen, Janet R. Vos, Nicoline Hoogerbrugge   +14 more
wiley   +1 more source

Genetic Landscape of Tinnitus in Cisplatin-Treated Testicular Cancer Patients: Implications for Personalized Medicine and Auditory Health Surveillance. [PDF]

Asian Pac J Cancer Prev
Barahman M, Shahbazi A, Pourkazemi M, Masoudi A, Neamatzadeh H.   +4 more
europepmc   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, EarlyView.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source