Results 31 to 40 of about 60,819 (286)

Myoid gonadal stromal tumor of the testis—the novel subtype of testicular gonadal stromal tumors: a case report and review of the literature

Journal of Medical Case Reports
Background Sex cord gonadal stromal tumors compose less than 10% of all testicular neoplasms and consist of a variety of histological subtypes. In 2016, the World Health Organization introduced a novel subtype, the myoid gonadal stromal tumor, that ...
Klaus-Peter Dieckmann, Lars Tharun, Markus Angerer, Alexander Harms, Christian Wülfing   +4 more
doaj   +1 more source

A RETROSPECTIVE OBSERVATIONAL CHART ANALYSIS OF PATIENTS UNDERGOING RADICAL ORCHIDECTOMY AT A REGIONAL LEVEL HOSPITAL.

Student's Journal of Health Research Africa, 2023
Background  The global incidence of testicular cancer is on the rise, although it remains a rare cancer accounting for 0.5% of all malignancies. Among South African men there appears to be a higher-than-expected incidence in Indian men. Objectives  To
Tanaka Muzenda, Dr V. Ramloutan
doaj   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

A High‐Throughput AngioPlate Platform with Integrated AngioTEER for Modeling and Monitoring Renal Proximal Tubule Injury

Advanced Materials Technologies, EarlyView.
Renal tubular injury is a major contributor to kidney disease, yet remains poorly understood due to the lack of predictive models. This study presents a high‐throughput 3D renal proximal tubule model on the AngioPlate platform integrated with automated TEER measurements (AngioTEER), enabling real‐time monitoring of drug‐induced nephrotoxicity ...
Shravanthi Rajasekar, Anushree Chakravarty, Kimia Asadi Jozani, Brenda Truong, Matana Hendrickson, Ahmed Attia, Muna Sabouny, Anna Basatskaya, Sergi Clotet‐Freixas, Madeleine Ludlow, Alexander Sotra, Dawn S. Y. Lin, Feng Zhang, Boyang Zhang   +13 more
wiley   +1 more source

Loss of Nuclear Functions of HOXA10 Is Associated With Testicular Cancer Proliferation

Frontiers in Oncology, 2018
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported from previous transgenic mouse models and human inherited diseases. However, whether it also plays important roles in promoting the development of testicular
Ruiqi Chen, Ruiqi Chen, Haolong Li, Yinan Li, Ladan Fazli, Martin Gleave, Lucia Nappi, Xuesen Dong   +7 more
doaj   +1 more source

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

Advanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber   +10 more
wiley   +1 more source

Testicular Cancer in Children [PDF]

Cancer, 1980
Management of testis cancer in children differs from that in adults due to the histological types and varying tolerances to chemotherapy agents.Embryonal adrenocarcinoma (endodermal sinus tumor, Teilum's tumor) is a tumor of infancy and young children and less aggressive than other testis cancers.
openaire   +4 more sources

Inheritance and testicular cancer [PDF]

British Journal of Cancer, 1995
Statistical analysis of published data on the age of onset of germ cell tumours of the testis and of the prevalence of bilateral disease in familial and general cases suggest the following: 1. Patients with bilateral disease carry the same genetic predisposition as familial cases. 2.
PW Nicholson, SJ Harland
openaire   +3 more sources

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Caregiver Emotional Burden in Testicular Cancer Patients: From Patient to Caregiver Support

Frontiers in Endocrinology, 2019
Testicular cancer is the most common tumor in young males aged 15–40 years. The overall cure rate for men with testicular cancer is >90%, so a huge number of these patients will become testicular cancer survivors.
Silvia De Padova, Chiara Casadei, Alejandra Berardi, Tatiana Bertelli, Alessia Filograna, Maria Concetta Cursano, Cecilia Menna, Salvatore Luca Burgio, Amelia Altavilla, Giuseppe Schepisi, Sabrina Prati, Sandra Montalti, Michal Chovanec, Michal Chovanec, Giuseppe Luigi Banna, Luigi Grassi, Michal Mego, Michal Mego, Ugo De Giorgi   +18 more
doaj   +1 more source