Results 41 to 50 of about 120,920 (289)

Transient increases in intracellular calcium and reactive oxygen species levels in TCam-2 cells exposed to microgravity [PDF]

, 2017
The effects of microgravity on functions of the human body are well described, including alterations in the male and female reproductive systems. In the present study, TCam-2 cells, which are considered a good model of mitotically active male germ cells,
Catizone, A, Guarnieri, S, Mariggiò, M. A., Morabito, C, Ricci, G, Schiraldi, C   +5 more
core   +2 more sources

Testicular Cancer Among African American College Men: Knowledge, Perceived Risk, and Perceptions of Cancer Fatalism

American Journal of Men's Health, 2007
African American men present at later stages of testicular cancer and have higher mortality rates than Caucasian men. Lack of awareness, beliefs, and access to care may influence this disparity.
Barbara D. Powe PhD, RN, Louie Ross PhD, Donoria Wilkerson BS, Patrice Brooks BA, Dexter Cooper MPH   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Myoid gonadal stromal tumor of the testis—the novel subtype of testicular gonadal stromal tumors: a case report and review of the literature

Journal of Medical Case Reports
Background Sex cord gonadal stromal tumors compose less than 10% of all testicular neoplasms and consist of a variety of histological subtypes. In 2016, the World Health Organization introduced a novel subtype, the myoid gonadal stromal tumor, that ...
Klaus-Peter Dieckmann, Lars Tharun, Markus Angerer, Alexander Harms, Christian Wülfing   +4 more
doaj   +1 more source

Anti-Ma and anti-Ta associated paraneoplastic neurological syndromes: 22 newly diagnosed patients and review of previous cases [PDF]

, 2008
Background: Paraneoplastic neurological syndromes (PNS) are indirect remote effects of cancer on the nervous system, often associated with the presence of specific serum antibodies.
Hoffmann, L. A., Jarius, S., Johannis, W., Koenig, F., Krumbholz, Markus, La Fougere, Christian, Newman, T., Pellkofer, Hannah Luise, Schueller, M., Vincent, A., Voltz, Raymond   +10 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Testicular Cancer Risk Awareness in Young Male

Revista Finlay, 2023
Foundation: testicular cancer is the most common malignant neoplasm in young men and early detection through testicular self-examination is essential. Objective: to evaluate the level of knowledge in young men about testicular cancer.
María Fernanda Cueva Moncayo, Lexter Mihalache, Edwin Marcelo Miranda   +2 more
doaj  

Prognostic features and markers for testicular cancer management

Indian Journal of Urology, 2010
Testicular neoplasm accounts for about 1% of all cancers in men. Over the last 40 years, the incidence of testicular cancer has increased in northern European male populations for unknown reasons.
Eddy S Leman, Mark L Gonzalgo
doaj   +1 more source

Over-reassurance and undersupport after a 'false alarm': a systematic review of the impact on subsequent cancer symptom attribution and help seeking [PDF]

, 2015
This literature review examined research into the impact of a previous 'all-clear' or non-cancer diagnosis following symptomatic presentation ('false alarm') on symptom attribution and delays in help seeking for subsequent possible cancer ...
Renzi, C, Wardle, J, Whitaker, KL
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source