Results 61 to 70 of about 120,920 (289)

Risk of childhood and adolescent, and young adult cancer in offspring of men with testicular cancer: A Danish nationwide study

International Journal of Cancer, EarlyView.
What's New? Testicular germ cell cancer (TC), the most common solid tumor among young men in Western countries, has survival rates exceeding 95 percent, allowing most survivors to pursue fatherhood. Concerns remain, however, about cancer risk in offspring, given potential mutagenic effects incurred during treatment for TC.
Mikkel Bandak, Susanne Rosthøj, Gitte Lerche Aalborg, Jakob Lauritsen, Aleksander Giwercman, Hege Sagstuen Haugnes, Gedske Daugaard, Allan Jensen   +7 more
wiley   +1 more source

Testicular cancer: The Most Common Malignancy in Young Men – A Review of Current Knowledge on Diagnosis and Treatment

Journal of Education, Health and Sport
Background. Testicular cancer is a rare malignancy that primarily affects young men and requires early diagnosis. The diagnosis is based on clinical tests, imaging tests and measurement of tumor markers. Treatment consists mainly of surgery, and further
Kamila Krycia, Karolina Mazur , Karolina Różycka , Magdalena Mulawa, Aleksandra Gałuszka, Emilia Piaszczyńska , Dominika Matacz , Sandra Drabik, Maja Gałuszka , Adrianna Adamczyk   +9 more
doaj   +1 more source

Loss of Nuclear Functions of HOXA10 Is Associated With Testicular Cancer Proliferation

Frontiers in Oncology, 2018
Background: HOXA10 is a key transcriptional factor that regulates testis development as reported from previous transgenic mouse models and human inherited diseases. However, whether it also plays important roles in promoting the development of testicular
Ruiqi Chen, Ruiqi Chen, Haolong Li, Yinan Li, Ladan Fazli, Martin Gleave, Lucia Nappi, Xuesen Dong   +7 more
doaj   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui, Adrian Florea, Leila Tekaya   +2 more
wiley   +1 more source

RISK FACTORS OF TESTICULAR CANCER IN ARIFIN ACHMAD REGIONAL GENERAL HOSPITAL, PEKANBARU, RIAU PROVINCE, INDONESIA

National Journal of Medical Research, 2019
Objective: To evaluate the incidence rate, patient profile, and risk factors of testicular cancer patients. Materials & methods: We reviewed the medical records of incidence rate, patient profile, and risk factor of testicular cancer patients in ...
Zuhirman Zamzami
doaj  

Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche. [PDF]

, 2017
A major challenge in stem cell differentiation is the availability of bioassays to prove cell types generated in vitro are equivalent to cells in vivo. In the mouse, differentiation of primordial germ cell-like cells (PGCLCs) from pluripotent cells was ...
Chen, Di, Clark, Amander T, Hennebold, Jon D, Lam, Truong N, Meistrich, Marvin L, Mitchell, Jennifer M, Orwig, Kyle E, Peters, Karen A, Rojas, Ernesto J, Shetty, Gunapala, Sosa, Enrique, Sukhwani, Meena, Tailor, Ramesh C, Wu, Zhuang   +13 more
core   +2 more sources

The Effects of Angiotensin Receptor Neprilysin Inhibitor on Endoplasmic Reticulum Stress in Doxorubicin‐Mediated Cardiomyopathy‐Associated Heart Failure Model in Rats

Journal of Applied Toxicology, EarlyView.
ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan, Meryem İlkay Karagül, Hatice Oruç Demirbağ, Ebru Balli   +3 more
wiley   +1 more source

Evaluation of Men’s Knowledge, Attitude and Behavior About Testicular Self-Examination and Testicular Cancer

Florence Nightingale Journal of Nursing, 2019
Aim: In this study evaluation of men’s knowledge, attitudes and behaviors about testicular self-examination and testicular cancer were planned. Method: This study was a descriptive-cross sectional study took place in Aydın Health School among nursing
Hossein ASGAR POUR, Rahşan ÇAM
doaj  

Is male infertility a forerunner to cancer?

International Brazilian Journal of Urology, 2010
PURPOSE: The frequency of testicular cancer and male infertility has been increasing in the past several decades. This article examines the relationship between male infertility and testicular cancer, concentrating particularly on causal links.
Whitney R. Burns, Edmund Sabanegh, Rima Dada, Brandon Rein, Ashok Agarwal   +4 more
doaj   +1 more source