Results 161 to 170 of about 70,701 (334)
Trends in the incidence of testicular germ cell tumors in the United States [PDF]
Katherine A. McGlynn+5 more
openalex +1 more source
PARP Inhibitors in Genitourinary Cancer: A New Paradigm Beyond Prostate Cancer
ABSTRACT Alterations in the homologous recombination repair genes, such as BRCA1 and BRCA2, are prevalent in various cancers, presenting a unique opportunity to develop synthetic lethal strategies that target homologous recombination deficiency (HRD).
Yohei Okuda+8 more
wiley +1 more source
Genome profiles of familial/bilateral and sporadic testicular germ cell tumors [PDF]
Sigrid Marie Kraggerud+7 more
openalex +1 more source
ABSTRACT Introduction Retroperitoneal lymph node dissection (RPLND) may be considered after chemotherapy or as primary treatment in patients with metastatic testicular cancer. We aimed to perform a systematic review to analyze outcomes in survivors across the domains of sexual, physical, and psychological function.
Gavin G. Calpin+4 more
wiley +1 more source
The fate of germ cells in cryptorchid testis
Cryptorchidism in males constitutes a notable risk factor for both infertility and testicular cancer. Infertility in adulthood is closely linked to the germ cell status in childhood.
Jorgen Thorup+9 more
doaj +1 more source
Frequent Fas Gene Mutations in Testicular Germ Cell Tumors [PDF]
Hitoshi Takayama+7 more
openalex +1 more source
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge+10 more
wiley +1 more source
Biomarkers for Salvage Therapy in Testicular Germ Cell Tumors. [PDF]
Urbini M+6 more
europepmc +1 more source
Germ cell and other tumors in individuals with differences in sex development
Abstract Approximately one in 3500 to one in 5100 live‐born infants have atypical external genital development, known as differences in sex development (DSD). In 2005, an expert consensus conference thoroughly reviewed aspects of health care for individuals with DSD.
Selma Feldman Witchel+1 more
wiley +1 more source
A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors
P. Voorhoeve+15 more
semanticscholar +1 more source