Results 141 to 150 of about 5,359,290 (244)

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

open access: yesAndrology, Volume 14, Issue 7, Page 2274-2279, October 2026.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor   +6 more
wiley   +1 more source

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

open access: yesAndrology, Volume 14, Issue 7, Page 1906-1928, October 2026.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede   +11 more
wiley   +1 more source

Doxorubicin and 4‐Hydroperoxycyclophosphamide Alter Mitochondrial Dynamics and miR‐34 Expression in Spermatogonia and Spermatocytes In Vitro

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Doxorubicin (DOX) and cyclophosphamide (CP) are widely used chemotherapeutic agents with known gonadotoxic effects. Since miRNAs play a key role in the transcriptional regulation of spermatogenesis, they are suggested as biomarkers for male infertility.
Hülya Öztatlıcı   +4 more
wiley   +1 more source

Signalling events controlling early cell fate decisions in a human embryonal carcinoma cell line, with relation to neural versus non-neural transitions m human ectoderm development [PDF]

open access: yes, 2007
In this study the human embryonal carcinoma cell line TERA2.cl.spl2 (TERA2.spl2) was utilised as an in vitro model in which to study mechanisms governing neural versus non- neural transitions in the human ectoderm.
Horrocks, Grace Mary
core  

A novel classification of testicular sex cord‐stromal tumours from the Testicular Sex Cord‐Stromal Tumour (TESST) group: a collaboration of the Genitourinary Pathology Society (GUPS) and the International Society of Urological Pathology (ISUP)

open access: yesHistopathology, Volume 89, Issue 4, Page 638-649, October 2026.
The TESST classification of testicular sex cord‐stromal tumours was agreed upon by consensus based on the best available evidence. The picture shows the members of the TESST group and delegates of GUPS and ISUP present in‐person at the first meeting of the group held at Johns Hopkins Hospital (Baltimore, 2024). Aims Testicular sex cord‐stromal tumours (
Andres M. Acosta   +29 more
wiley   +1 more source

Testicular germ cell tumors.

open access: yesJournal of B.U.ON. : official journal of the Balkan Union of Oncology, 2010
Testicular cancer is the most frequent solid tumor in young male adults and a disease with elusive pathogenesis. Germ cell tumors represent 95% of all testicular cancers. There was an increasing incidence of testicular germ cell tumors during the second half of the 20th century.
N, Diamantopoulos, A, Kortsaris
openaire   +1 more source

Bilateral Leydig Cell Tumor in a Capuchin Monkey (Sapajus apella): Case Report

open access: yesJournal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Leydig cell tumors (LCTs) are uncommon in nonhuman primates (NHPs). A bilateral LCT was identified in a 20‐year‐old male capuchin monkey (Sapajus apella) maintained under human care. Ultrasonography revealed a right testicular nodule, while necropsy identified bilateral testicular masses. Histopathology confirmed bilateral LCT.
Ewerton Lourenço Barbosa Favacho   +6 more
wiley   +1 more source

Metachronous bilateral testicular germ cell tumors: Report of two cases

open access: yes, 2010
Metachronous bilateral testicular germ cell tumors is a rare known problem. However, no report of metachronus bilateralism was identified in the PubMed database published from India so far, where testicular cancer is relatively rare.
Kumar, Aswin   +3 more
core   +1 more source

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