Results 131 to 140 of about 5,359,290 (244)

i(12p)-negative testicular germ cell tumors: A different group?

, 1988
Cytogenetic analysis was performed of three seminomas, two primary nonseminomas, and two mature residual teratomas following chemotherapy, all lacking i(12p).
Buist, Janneke, Sleijfer, Dirk T., Idenburg, Vera J., Seruca, Raquel, Castedo, Sérgio M. M. J., De Jong, Bauke, Oosterhuis, J. Wolter   +6 more
core   +1 more source

Protective Effects of Lactobacillus‐Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli–Infected Rats

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A Lactobacillus‐derived probiotic and postbiotic mixture alleviates E. coli–induced renal and reproductive dysfunction by modulating oxidative stress, inflammatory responses, and apoptosis, leading to improved tissue integrity and sperm quality. ABSTRACT Background Escherichia coli infections of the genitourinary tract are a major cause of renal and ...
Saeid Sedghi, Zahra Keshtmand, Saba Hosseini   +2 more
wiley   +1 more source

Cytogenetics of testicular germ cell tumors of adults

, 1998
In this article, not intended to be a review of the literature, we present our view about the oncogenesis, pathogenesis and tumor progression of testicular germ cell tumors of adults.
de Jong, B, van Echten, J
core   +1 more source

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas, Judy Y. Ou, Todd Alonzo, Logan G. Spector, Negar Fallahazad, Emily Owens, Anne C. Kirchhoff, Adam L. Green   +7 more
wiley   +1 more source

The fate of germ cells in cryptorchid testis

Frontiers in Endocrinology
Cryptorchidism in males constitutes a notable risk factor for both infertility and testicular cancer. Infertility in adulthood is closely linked to the germ cell status in childhood.
Jorgen Thorup, Jorgen Thorup, Simone Hildorf, Andrea E. Hildorf, Jonas M. Baastrup, Linn Salto Mamsen, Claus Yding Andersen, Tina E. Olsen, Dina Cortes, Dina Cortes   +9 more
doaj   +1 more source

Cancer Risk in Marfan Syndrome: A Swedish Population‐Based Cohort Study

International Journal of Cancer, Volume 159, Issue 7, Page 1707-1714, 1 October 2026.
The cancer risk in Marfan syndrome, an autosomal dominant connective tissue disorder, largely remains to be explored. In this population‐based matched cohort study of 1544 Swedish patients, the overall cancer risk in adults with Marfan syndrome showed no significant increase, except for the risk of endocrine tumours with a nearly threefold increase ...
Ida Nordgren, Anna Skarin Nordenvall, Alexandra Wachtmeister, Fulya Taylan, Yunxia Lu, Christina Norrby, Anna Lindstrand, Giedre Grigelioniene, Giorgio Tettamanti   +8 more
wiley   +1 more source

Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer

MedComm, Volume 7, Issue 10, October 2026.
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta, Ramakrishna Vadde, Ganji Purnachandra Nagaraju   +2 more
wiley   +1 more source

Infantile and adult testicular germ cell tumors: a different pathogenesis?

, 2002
Most adult testicular germ cell tumors have a characteristic chromosomal abnormality that is an isochromosome 12p [i(12p)]. Furthermore. these tumors are characterized by a chromosome number in the triploid range and gains and losses of (parts of ...
Timmer, A, van der Veen, AY, Molenaar, WM, de Jong, B, van Echten, J   +4 more
core  

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

Andrology, Volume 14, Issue 7, Page 2166-2179, October 2026.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu, Meng‐Li Cui, Wen‐Jing Yuan, Jia‐Ning Zhang, Shuo Zhang, Xi‐Qiao Yao, Ruo‐Qing Li, Jin‐Feng Li, En‐Zhong Li   +8 more
wiley   +1 more source