Results 71 to 80 of about 21,990 (240)

Leydig cell tumor of testis in a child: An uncommon presentation

open access: yesJournal of Indian Association of Pediatric Surgeons, 2017
Leydig cell tumors (LCTs) are rare testicular tumors. Incidence is 1%–3% of all testicular neoplasms, bilateral in 10%. They are frequently hormonally active, leading to feminizing or virilizing syndromes.
Madhumita Mukhopadhyay   +5 more
doaj   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature

open access: yesHistopathology, EarlyView.
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci   +20 more
wiley   +1 more source

Testicular mass frozen section examination: Pathological insights and diagnostic accuracy

open access: yesHistopathology, EarlyView.
Frozen section examination on testicular excisional biopsy is accurate and can help avoid unnecessary radical orchidectomy. A very high concordance rate between frozen section diagnosis and permanent diagnosis was obtained with no false negatives.
Roselyne Choiniere   +3 more
wiley   +1 more source

Prospective inter‐individual analysis of quality‐adjusted life years (QALYs) in brain tumor patients: A comprehensive assessment of health preferences

open access: yesInternational Journal of Cancer, Volume 158, Issue 5, Page 1250-1261, 1 March 2026.
What's New? Eloquent intracranial tumors present unique challenges in neurosurgical treatment due to their proximity to critical functional areas of the brain. This prospective, single‐center cohort study quantified real‐time changes in patients' subjective burden of health impairments using the Time Trade‐Off and Standard Gamble methods, providing ...
Lisa S. Hönikl   +4 more
wiley   +1 more source

On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer

open access: yesFrontiers in Endocrinology, 2019
Human primordial germ cells (PGCs) have been described in the yolk sac wall around the beginning of the third week. From week 4 to 5, they migrate under control of SCF/c-KIT signaling pathway to the genital ridge, where they become gonocytes.
Tiziano Baroni   +6 more
doaj   +1 more source

Primary Mucinous Borderline Tumor of the Testis: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Testicular mucinous borderline tumor is a rare primary testicular neoplasm with a generally favorable prognosis. Herein, we report a case diagnosed after high orchiectomy, with a brief literature review. Case Presentation A 77‐year‐old man presented with discomfort in the left scrotum.
Takeshi Shirota   +5 more
wiley   +1 more source

Clinical Characteristics of Testicular Nonseminomatous Germ Cell Tumor from West China: A 10-Year Experience of a Super regional Center [PDF]

open access: gold, 2019
Zeyu Chen   +9 more
openalex   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos   +4 more
wiley   +1 more source

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