Results 71 to 80 of about 70,701 (334)
DNA methylation profiling as a tool for testicular germ cell tumors subtyping.
Epigenomics, 2018 AIM Assess differential patterns of selected five genes' promoter methylation among testicular germ cell tumors (TGCT) subtypes. MATERIALS & METHODS CRIPTO, HOXA9, MGMT, RASSF1A and SCGB3A1 promoter methylation levels were evaluated by quantitative ...
Ana L. Costa +11 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet
Xiehe Yixue Zazhi, 2022 Objective To summarize and analyze the disease spectrum of testicular and adnexal lesions in Tibetan patients in Tibet Autonomous Region. Methods The relevant data of all Tibetan patients with testicular and adnexal lesions diagnosed by pathology in ...
LUO Hanhuan +5 more
doaj +1 more source
Extra-gonadal germ cell tumour – what about the testis! [PDF]
, 2011 Extra-gonadal germ cell tumours (EGGCT) are rare. Therefore further investigations of the testis is aimed at sourcing a possible primary origin of gonadal tumour. Over the years, various case series on EGGCT have been reported questioning its true nature
Christopher CKH, +5 more
core
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. [PDF]
, 2015 Correct orientation of the mitotic spindle in stem cells underlies organogenesis. Spindle abnormalities correlate with cancer progression in germ line-derived tumors.
Bucko, Paula +8 more
core +1 more source
Congenital malformations and testicular germ cell tumors [PDF]
International Journal of Cancer, 2013 Cryptorchidism is one of the few known risk factors for testicular germ cell tumors (TGCT). It has been postulated that other congenital malformations, in particular hypospadias, are also associated with increased risk; however, associations with birth defects have not been extensively studied. Using Swedish population-based registries we evaluated the
Olof Akre +5 more
openaire +4 more sources
Advanced Science, EarlyView.This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu +7 more
wiley +1 more source
Biomolecular Concepts, 2015 Testicular germ cell cancer manifests mainly in young adults as a seminoma or non-seminoma. The solid tumors are preceded by the presence of a non-invasive precursor cell, the carcinoma in situ cell (CIS), which shows great similarity to fetal germ cells.
Lawaetz Andreas C., Almstrup Kristian
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objective: To evaluate the clinical presentation of testicular tumors and their histological pattern present in our setup. Study Design: Case series. Place and Duration of Study: Armed Forces Institute of Urology (AFIU) Rawalpindi, from Jul 2016 to
Badar Murtaza +6 more
doaj +1 more source
Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]
, 2017 Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di +7 more
core +2 more sources