Results 91 to 100 of about 179,138 (280)

Runs of homozygosity and testicular cancer risk [PDF]

, 2019
Background: Testicular germ cell tumour (TGCT) is highly heritable but > 50% of the genetic risk remains unexplained. Epidemiological observation of greater relative risk to brothers of men with TGCT compared to sons has long alluded to recessively ...
West, C, Townsend, P. A., Loveday, C, Park, J. Y., Litchfield, K, Ingles, SA, Srihari, N. N., Beesley, S., Welch, R, Lu, Y. J., Albanes, D, Dunning, A. M., Cybulski, C., Neuhausen, SL, Bloomfield, D., Douglas, F., Stockdale, A, West, C., Huddart, R. A., Baybrooke, J, Douglas, F, Muir, K, Askill, C., Albanes, D., Benlloch, S, Brown, R, Kogevinas, M, Newcomb, LF, Broderick, P, Haiman, C. A., Al Olama, A. A., Appel, W, Benlloch, S., Lessel, D., Hamdy, FC, Stanford, JL, Batra, J., John, EM, Sud, A., Cannon-Albrigh, L., Donovan, JL, Hong, A, Sreenivasan, T, Madhavan, K, Mazhar, D., Winkler, M., Sarwar, N., Teixeira, M. R., Hennig, I, Brown, R., Money-Kryle, J., Stuart, N, Bertelli, G., Batra, J, Joffe, J., White, J, Faust, G., Mehra, R, Rogers, P, Schleutker, J, Faust, G, Lamont, A, De Ruyck, K, Tangen, CM, Maier, C., Menegaux, F., Dunning, AM, Chakraborti, P., Claessens, F., Pandha, H., Easton, DF, Rustin, G., Kim, J., Kaneva, R., Khaw, K-T, Howard, G., Hamilton, R. J., Clements, J, Usmani, N, Sorensen, KD, Orr, N., Sreenivasan, T., Hatton, M., Gilby, E., Gale, J., Stuart, N., Rosenstein, B. S., Giles, G. G., Highley, M, Holroyd, A, Kibel, AS, Holroyd, A., Dudakia, D, Cybulski, C, Wiklund, F., Lessel, D, Schumacher, F. R., Barber, J., Howard, G, Gronberg, H, Cannon-Albrigh, L, Huddart, RA, Madhavan, K., Wolk, A, Rathmell, A, Mucci, L., Eeles, R., Stevens, VL, Hrounda, D, Neal, DE, Dominguez, MG, Kogevinas, M., Razack, A, Cole, D., Levy, M, Money-Kryle, J, Park, JY, Pathak, S, Hamid, A, Hamilton, RJ, Travis, R. C., Leahy, M, Wolk, A., Peto, J, Henderson, B. E., Srihari, NN, Brock, C, Henderson, BE, Koutros, S, Baybrooke, J., Chowdhury, S., Penney, K. L., Mucci, L, Woby, S, Razack, A., Stanford, J. L., Easton, D. F., Kote-Jarai, Z., Gale, J, Donovan, J. L., Butt, M., Mehra, R., Claessens, F, Giles, GG, Kaneva, R, Seckl, M, Haiman, CA, Maehle, L, Teixeira, MR, Al Olama, AA, Simmonds, P, Neal, D. E., Savage, P., Cancel-Tassin, G, Houlston, RS, McAteer, J, Broderick, P., Nordestgaard, BG, Pashayan, N, Schumacher, FR, Woby, S., Brenner, H., Wiklund, F, Rathmell, A., Menegaux, F, Hennig, I., Roobol, MJ, Hong, A., Brock, C., Dudakia, D., Khaw, K. T., Hatton, M, Clements, J., Kibel, A. S., Turnbull, C., Humber, C., Vega, A, Eeles, R, Schleutker, J., Sorensen, K. D., Muir, K., Gapster, S., Berndt, S. I., Rogers, P., Bertelli, G, Barber, J, Orr, N, Lamont, A., Cancel-Tassin, G., Stockdale, A., John, E. M., Humber, C, Appel, W., Usmani, N., Stevens, V. L., Conti, D. V., Neuhausen, S. L., Travis, RC, Kelly, K., Newcomb, L. F., Mazhar, D, Koutros, S., Bloomfield, D, Clark, P, Chanock, S, Maier, C, Hamdy, F. C., Askill, C, Chanock, S., Gronberg, H., Sarwar, N, Beesley, S, Kote-Jarai, Z, Brenner, H, Reid, A., Conti, DV, Ruyck, K., Winkler, M, Hrounda, D., Tangen, C. M., Rustin, G, Litchfield, K., Chowdhury, S, Lu, Y-J, Clark, P., Gapster, S, Sud, A, Ingles, S. A., Pathak, S., Thibodeau, SN, Kim, J, Roobol, M. J., Maehle, L., Pandha, H, Peto, J., Highley, M., Savage, P, Welch, R., Berndt, SI, Hamid, A., Gago Dominguez, Manuela, Reid, A, Rosenstein, BS, Loveday, C., Thibodeau, S. N., Townsend, PA, Levy, M., Butt, M, Turnbull, C, Pashayan, N., Cole, D, White, J., McAteer, J., Nordestgaard, B. G., Penney, KL, Houlston, R. S., Seckl, M., Chakraborti, P, Joffe, J, Vega Gliemmo, Ana, Leahy, M., Gilby, E, Kelly, K, Simmonds, P.   +263 more
core   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Testicular neoplasms in adolescents [PDF]

Cancer, 1964
M R, ABELL, F, HOLTZ
openaire   +2 more sources

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Benign Intratesticular Epidermoid Cyst of the Testis: Diagnostic Dilemma

Online Journal of Health & Allied Sciences, 2014
Intratesticular epidermoid cysts of the testis are rare benign lesions, comprising about 1-2% of all the testicular neoplasms. Clinically it may not be differentiated reliably from the most common malignant testicular tumours and poses a diagnostic ...
Kishor H Suryawanshi, Dhiraj B Nikumbh, Parvez Mujawar, Poonam Pagare, Shivraj N Kanthikar   +4 more
doaj  

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source

Tertiary Syphilitic Gumma Mimicking Testicular Neoplasms. [PDF]

Cureus, 2023
Angerer M, Lübbersmeyer F, Gübitz R, Wülfing C, Dieckmann KP.   +4 more
europepmc   +1 more source

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

Andrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby, Sylvianne Hennebicq, Jacqueline Saias, Florence Brugnon, Isabelle Berthaut, Myriam Daudin, Louis Bujan, Ludovic Dumont, Christine Rondanino, Aurélie Feraille, Nathalie Rives   +10 more
wiley   +1 more source

Testicular neoplasms: the interrelationships of serum levels of microRNA-371a-3p (M371) and classical tumor markers with histology, clinical staging, and age-a statistical analysis. [PDF]

J Cancer Res Clin Oncol, 2023
Dieckmann KP, Dumlupinar C, Grobelny F, Utschig J, Klemke M, Ahmed Saad EM, Wülfing C, Pichlmeier U, Isbarn H, Belge G.   +9 more
europepmc   +1 more source

Testis-Sparing Surgery for Metachronous Testicular Tumor Following Orchiectomy. [PDF]

IJU Case Rep
ABSTRACT Introduction For metachronous bilateral testicular tumors occurring in young adulthood, the post‐treatment quality of life must be considered when making treatment decisions. Case Presentation A 46‐year‐old man presented to our hospital with a chief complaint of two bean‐sized hard masses palpable in the right testis.
Tobiume M, Nishikawa G, Aoki S, Morinaga S, Yamada Y, Yamada E, Buma Y, Ogawa H, Nakane S, Yamada Y.   +9 more
europepmc   +2 more sources