Results 81 to 90 of about 179,138 (280)

MicroRNA‐130a‐3p Targets the Androgen‐Related Transcription Factor MAFB: Effects on Proliferation, Migration, Apoptosis, and Cell Cycle in Hypospadias

Pediatric Discovery, EarlyView.
MicroRNA‐130a‐3p targets and inhibits MAFB expression, leading to the development of hypospadimas. MicroRNA‐130a‐3p inhibits the expression of MAFB, disrupts the normal processes of cell proliferation, migration, cell apoptosis, and cycle progression, and ultimately leads to the development of hypospadias.
Jiaxin Zhou, Yixuan Wang, Zhicheng Zhang, Qiang Zhang, Zhenmin Liu, Hongsong Chen, Xingguo Luo, Chunlan Long, Lianju Shen, Xing Liu, Guanghui Wei   +10 more
wiley   +1 more source

Epithelial Cell Adhesion Molecule (EpCAM) Expression in Human Tumors: A Comparison with Pan-Cytokeratin and TROP2 in 14,832 Tumors

Diagnostics
EpCAM is expressed in many epithelial tumors and is used for the distinction of malignant mesotheliomas from adenocarcinomas and as a surrogate pan-epithelial marker.
Anne Menz, Nora Lony, Maximilian Lennartz, Sebastian Dwertmann Rico, Ria Schlichter, Simon Kind, Viktor Reiswich, Florian Viehweger, David Dum, Andreas M. Luebke, Martina Kluth, Natalia Gorbokon, Claudia Hube-Magg, Christian Bernreuther, Ronald Simon, Till S. Clauditz, Guido Sauter, Andrea Hinsch, Frank Jacobsen, Andreas H. Marx, Stefan Steurer, Sarah Minner, Eike Burandt, Till Krech, Patrick Lebok, Sören Weidemann   +25 more
doaj   +1 more source

Primary borderline mucinous neoplasm of the testis: A case report and literature review

Indian Journal of Urology, 2012
Testicular/paratesticular neoplasms morphologically resembling surface epithelial tumors of ovarian type are rare neoplasms. The criteria for the diagnosis and nomenclature of these tumors parallels those used for ovarian homologues.
Santosh Menon, Sharique Ahmed, Sangeeta Desai   +2 more
doaj   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

A rare case of seminoma metastasis to the bladder

Вестник урологии
Introduction. The great majority of testis neoplasms are germ cell tumours. The most common site of metastasis is the retroperitoneal region. Metastasis to the bladder is very rare.Clinical case.
Muhamad Al-Tawil
doaj   +1 more source

A case of xanthogranulomatous orchitis and its preoperative diagnostic challenges

Urology Case Reports, 2020
Xanthogranulomatous orchitis (XGO) is an extremely rare inflammatory disease of the testis which can mimic testicular tumors. We report a 42-year-old man who presented with left scrotal swelling for one-month duration associated with pus discharge from ...
Khaled A. Murshed, Noheir M. Taha, Mohamed Ben-Gashir   +2 more
doaj   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Leydig Cell Tumors of the Testis with Massive Calcification- A Case Report and Literature Review

Caucasian Medical Journal
Leydig cell tumors (LCTs) are rare testicular neoplasms that arise from Leydig cells in the testicular interstitium. These tumors are typically benign and often secrete testosterone, leading to hormonal symptoms.
Wei Yang, Chendong He
doaj   +1 more source

Primary Carcinoid Tumor of the Testis

Case Reports in Urology, 2015
Primary carcinoid tumors of the testis are a rare entity comprising less than 1% of all testicular neoplasms. Their presence should be considered particularly when evaluating a testicular lesion in an older male patient. Immunohistochemical studies may
Albert A. Petrossian, Joseph Habibi, David E. Rapp, Dharamdas Ramnani   +3 more
doaj   +1 more source