Results 191 to 200 of about 179,138 (280)

Protective Effects of Luteolin Against Cisplatin‐Induced Hepatic and Renal Toxicity: Biochemical and Cellular Evidence

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Cisplatin induces oxidative stress and hepatotoxicity, as evidenced by increased serum biomarkers and oxidative damage parameters. Luteolin, derived from Pistacia terebinthus, mitigates these effects by enhancing antioxidant defense systems and improving cell viability in cancer cell lines.
Özge Temiz   +9 more
wiley   +1 more source

Emerging imaging modalities for the diagnosis of malignant lesions of the male reproductive tract in companion animals. [PDF]

open access: yesAnim Reprod
Gomes DR   +7 more
europepmc   +1 more source

Obeticholic Acid and Edaravone Protect Against Cisplatin‐Induced Hepatotoxicity Through Modulation of Keap1/Nrf2/ARE, TNF‐α/NF‐κB, and AKT/GSK‐3β Pathways

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
The graphical abstract explores the possible underlying molecular mechanisms of Obeticholic acid against hepatotoxicity induced by chemotherapy exposure. ABSTRACT Hepatotoxicity is one of the most crucial side effects of chemotherapy administration. Obeticholic acid (OCA) is a semisynthetic bile acid and farnesoid X receptor (FXR) agonist derived from ...
Fares E. M. Ali   +7 more
wiley   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng   +9 more
wiley   +1 more source

Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi   +6 more
wiley   +1 more source

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