Results 221 to 230 of about 179,138 (280)

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, Volume 105, Issue 3, Page 271-284, September 2026.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Comprehensive Profiling of Cell Surface Proteins in Testicular Germ Cell Tumors. [PDF]

Cancer Res Commun
Ebrahimi H, Moradi A, Barragan-Carrillo R, Zugman M, Jaime-Casas S, Shah K, Castro D, Mercier B, Li X, Hsu J, Zang PD, Nguyen CB, Tripathi A, Zhumkhawala A, Pal SK, Sadimin E, Dorff T, Chehrazi-Raffle A.   +17 more
europepmc   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, Volume 59, Issue 9, September 2026.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source

Extratesticular leiomyoma arising from the epididymis: Diagnostic challenges in a chronic scrotal mass. [PDF]

Urol Case Rep
Kamble R, Suhrid C, Pandya J, Kavishwar V.   +3 more
europepmc   +1 more source

Cancer survivorship in malignant melanoma

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 9, Page e1291-e1308, September 2026.
Summary Robust long‐term survival data have transformed the prognosis of metastatic melanoma. For combination therapy with immune checkpoint inhibitors (ICIs), 10‐year melanoma‐specific survival rates now exceed 50 %, and durable disease control is achievable in a substantial proportion of patients, including those with brain metastases.
Markus Reitmajer, Susanne Dugas‐Breit, Chiara L. Blomen, Elisabeth Livingstone, Max Schlaak, Markus V. Heppt, Michael M. Sachse, Madlen Hörold, Friedegund Meier, Sebastian Haferkamp, Christian Apfelbacher, Georgia Schilling, Andrea von den Berg, Frank Meiss, Lisa Zimmer, Andrea Forschner   +15 more
wiley   +1 more source

Prevalence of testicular disorders in dogs and cats in Fortaleza from 2020 to 2023. [PDF]

Anim Reprod
de Andrade ABP, Maia RKS, Moura MEDC, Silva HVR, da Silva LDM.   +4 more
europepmc   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, Volume 117, Issue 3, Page 642-652, September 2026.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Infertility as a possible diagnostic feature of Carney complex. [PDF]

JCEM Case Rep
Knoblovits P, Abelleira E, Valzacchi GR, Suárez SM, Costanzo PR, Kleppe S.   +5 more
europepmc   +1 more source

Use of Sildenafil Citrate for the Treatment of Erectile Dysfunction in Stallions: First Case Reports

Reproduction in Domestic Animals, Volume 61, Issue 9, September 2026.
ABSTRACT Pharmacological aids can be useful alternatives to enhance penile erection and/or improve ejaculatory function, thereby prolonging the reproductive life of stallions with ejaculatory disorders. This study aimed to evaluate the effects of sildenafil citrate in the treatment of erectile dysfunction and on semen quality in two aged stallions, a ...
Thaís Mendes Sanches Cavalero, Frederico Ozanam Papa, Gabriel Augusto Monteiro, Patrícia de Mello Papa, Felipe Pires Hartwig, Camila de Paula Freitas‐Dell'Aqua, Marco Antônio Alvarenga, Marcela Souza e Freitas, Yame Fabres Robaina Sancler‐Silva   +8 more
wiley   +1 more source