Results 31 to 40 of about 11,266 (247)

Diffuse testicular microlithiasis is associated with successful sperm retrieval in men with nonobstructive azoospermia

open access: yesF&S Reports
Objective: To evaluate whether ultrasonographic patterns of testicular microlithiasis are associated with sperm retrieval outcomes by microdissection testicular sperm extraction in men with nonobstructive azoospermia.
Yuji Tsuji, M.D., Ph.D.   +4 more
doaj   +1 more source

Innovations in surgical management of nonobstructive azoospermia

open access: yesIndian Journal of Urology, 2016
Testicular sperm extraction (TESE) technique and intra-cytoplasmic sperm injection are breakthrough fertility treatments for men with nonobstructive azoospermia (NOA).
Renzhong Ran   +2 more
doaj   +1 more source

Three cases of sperm immobility for intracytoplasmic sperm injection using testicular sperm

open access: yesIJU Case Reports
Introduction Sperm immobility is a condition in which sperm are viable but not motile. We reported three patients with sperm immobility, who underwent testicular sperm extraction‐intracytoplasmic sperm injection.
Noboru Mimura   +5 more
doaj   +1 more source

Testicular sperm extraction with intracytoplasmic sperm injection for nonobstructive azoospermia

open access: yesUrology, 1997
To provide fertility for men with nonobstructive azoospermia.A retrospective review of treatment results at a university infertility center was undertaken. Sixteen couples entered an attempted in vitro fertilization (IVF)-intracytoplasmic sperm injection (ICSI) cycle for treatment of nonobstructive azoospermia.
P N, Schlegel   +6 more
openaire   +2 more sources

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

Incidental seminoma in nonobstructive azoospermia: a case report

open access: yesF&S Reports
Objective: To report on the incidental finding of invasive seminoma in a patient with nonobstructive azoospermia during microdissection testicular sperm extraction. Design: Case report.
Jonathan Gal, MD   +3 more
doaj   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

open access: yesAdvanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li   +8 more
wiley   +1 more source

Observations of high variability in DNA fragmentation of epididymal sperm in men

open access: yesThe Canadian Journal of Urology
Objectives: Men with obstructive azoospermia (OA) or infertility often require surgical sperm retrieval for assisted reproductive techniques. While sperm can be successfully obtained from either the testis or epididymis in these patients, sperm DNA ...
Manish Kuchakulla   +5 more
doaj   +1 more source

Microdissection testicular sperm extraction in men with nonobstructive azoospermia: Experience of King Saud University Medical City, Riyadh, Saudi Arabia

open access: yesUrology Annals, 2017
Objectives: Microdissection testicular sperm extraction (micro-TESE) is an optimal technique of sperm extraction for intracytoplasmic sperm injection. This study is to present our experience in micro-TESE and evaluate the relation of its sperm retrieval ...
Saleh Binsaleh   +2 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

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