Results 51 to 60 of about 8,362,741 (232)

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

Prospective ultrasonographic study of blood flow and testicular volume in patients submitted to surgical repair of inguinal hernia without using prosthesis [PDF]

Acta Cirúrgica Brasileira, 2018
Purpose: To evaluate the behavior of arterial circulation and testicular volume in patients submitted to conventional inguinal hernia repair without the use of a synthetic prosthesis to reinforce the posterior wall. Methods: A prospective observational
Cláudio de Saboya David, Alberto Goldenberg   +1 more
doaj   +1 more source

Correlation Between Testicular Biometrics and Serum Level of Reproductive Hormones of Crossed Arewa Breed of Stallions in Ilorin, Nigeria

Media Kedokteran Hewan, 2022
The hypothalamic-pituitary-gonadal axis (HPG) controls the reproductive physiology activities of stallions. The organs involved in this axis are the hypothalamus, the pituitary, and the gonads (testes), and the endocrine secretions from these organs ...
Afisu Basiru, Ishola Olaide Abdullahi, Adah Sylvanus Adakole, Akorede Ganiu Jimoh, Aremu Abdulfatai, Azeez Oyebisi Mistura   +5 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

Advanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu, Shanyao Liu, Haixin Liang, Jiani Yang, Yanhe Li, Jiqing Yin, Xueguang Zhang, Yan Zhang, Dandan Bai, Zihui Yan, Zhuoao Zhang, Yanping Jia, Kuisheng Liu, Yifan Sheng, Jiani Xiang, Chenxiang Xi, Baoxing Dong, Xinyi Lei, Jiayu Chen, Hong Wang, Yi Guo, Yanping Zhang, Shaorong Gao, Wenqiang Liu   +23 more
wiley   +1 more source

COMPARISON OF TESTICULER VOLUMES BETWEEN NORMAL AND HEALTHY ASYMPTOMATIC ADOLESCENT WITH VARICOCELE BY SCROTAL ULTRASONOGRAPHY

Urology Research and Practice, 2019
In this study we compared ihe testicular volume and volume differences between healthy adolescents and healthy asymptomatic adolescents with clinically palpable (Grade 2 and Grade 3) varicoceles using scrotal ultrasound.
Ö. Özsan, E. Özbek, R. Kutlu, S. Yoloğlu, T. Zengin, T. Gürpınar   +5 more
doaj   +2 more sources

Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly

Advanced Science, EarlyView.
LENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Mingxing Zhang, Xin Wang, Yilan Teng, Zhicheng Wu, Jing Fan, Hongwen Zhu, Peng Dai   +6 more
wiley   +1 more source

THE EFFECT OF VARICOCELECTOMY ON TESTICULAR VOLUME IN INFERTILE PATIENTS WITH VARICOCELES [PDF]

The presence of a varicocele has been associated with decrease in testicular volume both in adult and pediatric patients. However, a study on the effect of varicocelectomy on testicular volume in the adult varicocele patient has never been reported.
KATSUNO, SATOSHI, YOKOI, KEISUKE, MIYAKE, KOJI, HIBI, HATSUKI, YAMAMOTO, MASANORI   +4 more
core   +2 more sources

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Volume alteration of undescended testes: Before and after orchiopexy

Urological Science, 2016
Objectives: We used ultrasound to investigate the volume of undescended testes before and after orchiopexy, and compared these data with normally descended testes. Materials and Methods: We retrospectively reviewed boys in the age range of 0–18 years who
Chi-Shin Tseng, Kuo-How Huang, Yeong-Shiau Pu, I-Ni Chiang   +3 more
doaj   +1 more source

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

Advanced Science, EarlyView.
DUET‐seq is an open‐source droplet platform that jointly profiles chromatin accessibility and gene expression from the same nucleus. Dissolvable dual‐linker hydrogel beads and a one‐step intra‐droplet RT‐PCR co‐index both modalities in under 12 h at roughly $0.04 per cell.
Dong Cheng, Zijun Meng, Lan Wei, Pingjing Yang, Fanfan Zhang, Zhiyi Luo, Ting Lai, Chunli Li, Mengyao Zhao, Mengqin Xu, Jiaqi Wang, Linjun Li, Huarong Chen, Jin Li, Ailong Huang, Youquan Bu, Liuyang Zhao   +16 more
wiley   +1 more source