Results 111 to 120 of about 25,819,872 (363)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

A massive binary black-hole system in OJ 287 and a test of general relativity [PDF]

open access: green, 2008
M. J. Valtonen   +25 more
openalex   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

DIFFERENTIAL REINFORCEMENT OF ALTERNATIVE BEHAVIOR INCREASES RESISTANCE TO EXTINCTION: CLINICAL DEMONSTRATION, ANIMAL MODELING, AND CLINICAL TEST OF ONE SOLUTION [PDF]

open access: bronze, 2010
F. Charles Mace   +6 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

TESTS COATINGS UNDER VARIABLE LOADS

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2017
The experimental laboratory-scale plant for the fatigue testing of samples with electrolytic coating were designed and constructed. Shows the kinematic scheme and considered the principle of the plant. The dependences for determination of test parameters
N. L. Venediktov   +2 more
doaj   +1 more source

A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses [PDF]

open access: gold, 2021
Bart Koopman   +8 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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