Results 91 to 100 of about 6,038,565 (279)

Methods for evaluating the effectiveness of trading strategies

open access: yesУченые записки Российской академии предпринимательства, 2021
This article will help you understand and prevent mistakes that traders in the evaluation of the effectiveness of trading strategies. The paper discusses both methods of assessing the effectiveness of trading strategies and the determination of their ...
E. A. Skryabin
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Manufacturing of Agricultural Machinery Metal Parts Using Additive Sheet Lamination Technology

open access: yesМеханика машин, механизмов и материалов
Possibilities and prospects are considered for application of additive sheet lamination technology for direct manufacturing of agricultural machinery metal parts on the example of manufacturing of plow steel beam.
Nikolay K. Tolochko   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

ABOUT THE NECESSARY AND SUFFICIENT CONDITION FOR THE EXISTENCE VALIDATION OF FUNCTIONAL TEST OF MINIMUM POSSIBLE LENGTH FOR A ONE-DIMENSIONAL ITERATIVE PATTERNS

open access: yesNauka ta progres transportu, 2007
The problem of confidence testing applying to the regular iterative circuits is considered. Total number of such circuits from one class is estimated.
O. I. Tymoshkin
doaj  

Method of testing the software of spacecraft electronic equipment based on fault injection in the algorithms of orientation and stabilization

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
The purpose of the work is to develop and describe a new method of testing spacecraft electronic equipment. The article substantiates the relevance of developing new methods and means of testing on-board electronic equipment of spacecraft based on the ...
D. A. Nedorezov   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On terminology awareness of the first-year physical education students

open access: yesВестник Северо-Кавказского федерального университета
Introduction. Successful development and constructive use of the conceptual and terminological apparatus are the most important conditions for ensuring high-quality educational and practical activities in the field of physical culture.Goal.
V. P. Lukyanenko   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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