Results 101 to 110 of about 6,038,565 (279)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Strengthening community engagement in the fight against hepatitis B in two regions of Cameroon

open access: yesJournal of Public Health in Africa
Background: In Cameroon, the prevalence of hepatitis B in the general population is 10%, and the vaccination coverage is less than 15% among adults. Although 80% have heard about the disease, only 50% know the modes of transmission and prevention of ...
Solange N.M. Atah   +15 more
doaj   +1 more source

Stay on target!: The evolution and application of automatic item generation to professional testing paradigms

open access: yes
Automatic item generation (AIG) was originally hailed as an innovative, software-enabled solution that would support the inexpensive development of thousands of items at the click of a button.

core  

Non-destructive testing of aerospace components

open access: yes, 1985
SIGLEAvailable from British Library Lending Division - LD:85/19388(Non-destructive) / BLDSC - British Library Document Supply CentreGBUnited ...
British Inst. of Non-Destructive Testing, Northampton (United Kingdom)
core  

Testing intelligent textiles

open access: yes, 2008
Intelligent textiles represent the next generation of fibers, fabrics and products made from them. In the last decade, research and development in smart/intelligent materials and structures have led to the birth of a wide range of novel smart products in
Hu, JL, J. Hu, Babu, KM, K.M. Babu
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

UA12/9 WKU Counseling & Testing Center, Vol. 5, Issue 2 [PDF]

open access: yes, 2018
Newsletter created by and about WKU Counseling & Testing ...
WKU Counseling & Testing Center
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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