Results 111 to 120 of about 6,038,565 (279)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Testing, testing [PDF]

open access: yesFrontline Gastroenterology, 2018
openaire   +2 more sources

Introduction to fabric testing

open access: yes, 2008
Fabric testing plays a crucial role in gauging product quality, assuring regulatory compliance and assessing the performance of textile materials. It provides information about the physical or structural properties and the performance properties of the ...
Hu, JL, J. Hu
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Preferences for models of sexual health service delivery among gay, bisexual and other men who have sex with men in Australia: a discrete choice experiment

open access: yesJournal of the International AIDS Society
Introduction Gay, bisexual and other men who have sex with men are disproportionately affected by HIV and other sexually transmitted infections (STIs). This study explores preferences for different models of sexual health services among gay, bisexual and
Jason J. Ong   +4 more
doaj   +1 more source

Testing Vision Is Not Testing For Vision

open access: yesTranslational Vision Science & Technology, 2019
Visual prostheses aim to restore, at least to some extent, vision that leads to the type of perception available for sighted patients. Their effectiveness is almost always evaluated using clinical tests of vision. Clinical vision tests are designed to measure the limits of parameters of a functioning visual system.
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Outreach to Outcomes: Advancing HIV Care in Priority Populations

open access: yesJournal of CME
The US HIV epidemic disproportionately affects historically marginalised groups, particularly Black individuals in the Southern states. The national “Ending the HIV Epidemic” (EHE) initiative was established in 2019 to reduce HIV infections in priority ...
Lesley Simon   +5 more
doaj   +1 more source

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