Results 51 to 60 of about 1,542,868 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fatigue strength assessment of SUS316 by small bulge fatigue (SBF) test

Ubiquity Proceedings, 2018
A new fatigue test apparatus with a small disk-type specimen (8 mm in diameter) was developed in the authors’ group. This testing technique was termed “Small Bulge Fatigue (SBF) test”.
S. Komazaki, R. Jojima, N. Muraoka, S. Nogami, M. Kamaya, C. Hisaka, M. Fujiwara, A. Nitta   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Hydrophobic monomer systems for dental composites: development and physicochemical evaluation of UDMA/IBOMA formulations

BMC Oral Health
Background The objective of this study was to evaluate UDMA/IBOMA formulations at varying ratios as hydrophobic alternatives to conventional Bis-GMA/TEGDMA dental resin composites, assessing hydrophobic properties, polymerization efficiency, mechanical ...
Shaiva Thakar, Marc Hayashi, Zaher Jabbour, Reuben Kim, Shahed Al Khalifah, Deukwon Jo, Mijoo Kim   +6 more
doaj   +1 more source

Implicit video feedback produces positive changes in landing mechanics

Journal of Experimental Orthopaedics, 2018
Background Implicit (IF) and explicit (EF) feedback are two motor learning strategies demonstrated to alter movement patterns. There is conflicting evidence on which strategy produces better outcomes.
Tijana Popovic, Shane V. Caswell, Anne Benjaminse, Tarique Siragy, Jatin Ambegaonkar, Nelson Cortes   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Growth, Feed Utilization, Lipid Metabolism, and Metamorphosis of Bullfrog (Aquarana catesbeianus) Tadpoles Fed Diets With Different Lipid Levels

Aquaculture Nutrition
This study investigated the effect of dietary lipid levels on growth performance, lipid metabolism, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog (Aquarana catesbeianus) tadpoles.
Juan Gao, Ling Wang, Jian Zhang, Kangle Lu, Kai Song, Xueshan Li, Chunxiao Zhang   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The role of a best practice alert in the electronic medical record in reducing repetitive lab tests

ClinicoEconomics and Outcomes Research, 2018
Harini Bejjanki,1 Lazarus K Mramba,2 Stacy G Beal,3 Nila Radhakrishnan,1 Rohit Bishnoi,1 Chintan Shah,1 Nikhil Agrawal,4 Neil Harris,3 Robert Leverence,1 Kenneth Rand3 1Division of Hospital Medicine, Department of Medicine, University of Florida ...
Bejjanki H, Mramba LK, Beal SG, Radhakrishnan N, Bishnoi R, Shah C, Agrawal N, Harris N, Leverence R, Rand K   +9 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source