Results 61 to 70 of about 28,663 (219)
The role of a best practice alert in the electronic medical record in reducing repetitive lab tests
ClinicoEconomics and Outcomes Research, 2018 Harini Bejjanki,1 Lazarus K Mramba,2 Stacy G Beal,3 Nila Radhakrishnan,1 Rohit Bishnoi,1 Chintan Shah,1 Nikhil Agrawal,4 Neil Harris,3 Robert Leverence,1 Kenneth Rand3 1Division of Hospital Medicine, Department of Medicine, University of Florida ...
Bejjanki H +9 more
doaj
BMC Oral HealthBackground The objective of this study was to evaluate UDMA/IBOMA formulations at varying ratios as hydrophobic alternatives to conventional Bis-GMA/TEGDMA dental resin composites, assessing hydrophobic properties, polymerization efficiency, mechanical ...
Shaiva Thakar +6 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Surface Modification Technologies for Space and Planetary Applications
Mechanics and Advanced TechnologiesThis paper presents an overview of processes developed in our company for applications in various space and planetary environments. A number of materials including polymers, paints and other organic-based materials undergo dramatic changes and ...
Якоб Клеймен
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Evaluation of Laboratory Tests [PDF]
New England Journal of Medicine, 1968 W, Kaufmann, R E, Vanderlinde
openaire +5 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source