Results 91 to 100 of about 5,262,635 (292)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The influence of hydrostatic pressure on the interlaminar fracture toughness of carbon/epoxy composites [PDF]
, 2006 The use of composites for deep sea applications requires a thorough understanding of the behaviour of these materials. While several studies have examined the influence of pressure on in-plane properties few data are available for the interlaminar ...
Peleau, M. +3 more
core +1 more source
Industrial test of a 6-m long bearing steel ingot by electroslag remelting withdrawing process [PDF]
China Foundry, 2015 In this study, the key technologies of a 6-m long bearing steel ingot produced by electroslag remelting withdrawing (ESRW) process, including bifilar mode supply, slag system development, and design of mold, were studied based on the laboratory research ...
Xi-min Zang, Tian-yu Qiu, Xin Deng
doaj
Applied Sciences, 2019 Ultrasonic Lamb wave testing has been successfully applied in nondestructive testing. However, because of Lamb wave multimodal and dispersion characteristics, the received signals are often multimodal and overlapping, which makes them very complicated ...
Xiao Chen, Dandan Ma
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Educational Testing Service : Students, Institutions, and Programs
, 1975 (br.)Notes (part.
Educational Testing Service
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Testing the mode of quark condensation
Physics Letters B, 1986 Abstract If unconventional quark condensates are considered as possibilities, pions may acquire mass m π ≠0 only after d orders of perturbation in the quark-mass operator. Then ππ scattering amplitudes are given by F π −2 {( q i + q j ) 2 + ζ d m π 2 ] for small pion momenta q i ( F π ≈93MeV), where ζ 1 =−1 and ...
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source