Results 71 to 80 of about 5,262,635 (292)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A subset of precise UML for Model-based Testing [PDF]

open access: yes, 2007
This paper presents an original model-based testing approach that takes a UML behavioural view of the system under test and automatically generates test cases and executable test scripts according to model coverage criteria.
Legeard, B   +19 more
core   +1 more source

Design and implementation of an intelligent production testing platform with dual mode modules for power and IoT

open access: yesDianzi Jishu Yingyong
According to the strategic requirements of the country for new quality productivity of enterprises, and with the increasing development of power grid intelligence, the demand for dual-mode modules equipped with low-power wireless communication channels ...
Song Di, Xiao Deyong, Hao Weiqi, Luo Dan
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Recent advancements in Lorentz force eddy current testing [PDF]

open access: yes, 2016
Lorentz Force Eddy Current Testing (LET) is a non-destructive testing technique based on induced eddy currents due to relative motion between a permanent magnet and a conductive, non-ferromagnetic device under test which has been recently introduced. The
Weise, Konstantin   +5 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Functional Testing Approaches for "BIFST-able" tlm_fifo [PDF]

open access: yes, 2008
Evolution of Electronic System Level design methodologies, allows a wider use of Transaction-Level Modeling (TLM). TLM is a high-level approach to modeling digital systems that emphasizes on separating communications among modules from the details of ...
Navabi, Z.   +9 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A new test methodology based on structural resonance for mode I fatigue delamination growth in an unidirectional composite [PDF]

open access: yes, 2013
A specific device has been set up to test by vibration resonance the mode I fatigue delamination growth onset of composite laminates. This test system, based on the DCB test specimen, is a mass-spring-specimen dynamic system designed to resonate.
Rico, Germain   +4 more
core   +1 more source

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