Advanced Science, EarlyView.Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu +13 more
wiley +1 more source
Lifelong testicular differentiation in
Reproductive Biology and Endocrinology, 2009 Background In numerous Caudata, the testis is known to differentiate new lobes at adulthood, leading to a multiple testis. The Iberian ribbed newt Pleurodeles waltl has been studied extensively as a model for sex determination and differentiation ...
Chesnel Amand +3 more
doaj +1 more source
Effect of competitive cues on reproductive morphology and behavioral plasticity in male fruitflies [PDF]
, 2015 Phenotypic plasticity will be favored whenever there are significant fitness benefits of responding to environmental variation. The extent and nature of the plasticity that evolves depends on the rate of environmental fluctuations and the capacity to ...
Bretman, Amanda +3 more
core +1 more source
Fluid dynamic design for mitigating undesired cell effects and its application to testis cell response testing to endocrine disruptors [PDF]
, 2023 Seungjin Lee +7 more
openalex +1 more source
CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human
Advanced Science, EarlyView.This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan +21 more
wiley +1 more source
Efek ekstrak testis terhadap jumlah implantasi dan jumlah anak pada mencit (Mus musculus)
Journal of Biological Researches, 2012 Extract of testis contains the testis specific proteins. The testis proteins may raise immune responses. The immune responses arethe antibodies against testis specific anti-protein.
Sri Puji Astuti Wahyuningsih +2 more
doaj +1 more source
Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]
, 2011 In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo +6 more
core +2 more sources
Advanced Science, EarlyView.This study investigates the role of PACS‐2 in IDD, demonstrating that it suppresses the nuclear translocation of SP1, thereby downregulating its downstream target LRRK2. This reduces LRRK2‐mediated ubiquitination and degradation of Mfn2 through the JNK pathway, preserving MAM integrity and promoting NPSC survival.
Liang Kang +19 more
wiley +1 more source
SEASONAL INCIDENCE OF CAPTURE AND REPRODUCTION OF FIVE FOSSORIAL SNAKE SPECIES IN WEST VIRGINIA [PDF]
, 2017 Museum specimens of five species of fossorial snakes collected in West Virginia during 1930–2000 were examined to determine monthly incidence of capture, adult body sizes, reproductive cycle, and clutch characteristics.
Herrick, Kelli-Marie +3 more
core +2 more sources
Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids
Advanced Science, EarlyView.To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun +9 more
wiley +1 more source