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Testis Development [PDF]

open access: yesEndocrine Reviews, 2018
Production of sperm and androgens is the main function of the testis. This depends on normal development of both testicular somatic cells and germ cells. A genetic program initiated from the Y chromosome gene sex-determining region Y (SRY) directs somatic cell specification to Sertoli cells that orchestrate further development.
Juho-Antti Mäkelä   +3 more
openaire   +2 more sources

Testicular endocrine activity is upregulated by D-Aspartic acid in the green frog Rana esculenta [PDF]

open access: yes, 2004
This study investigated the involvement of D-aspartic acid (D-Asp) in testicular steroidogenesis of the green frog Rana esculenta and its effect on stimulation of thumb pad morphology and glandular activity, a typical testosterone-dependent secondary ...
ASSISI, LOREDANA   +5 more
core   +1 more source

Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice

open access: yesStem Cell Research & Therapy, 2018
Background Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) is only 12%, the ...
Prashant Kadam   +5 more
doaj   +1 more source

Comparative Transcriptome Analysis of Differentially Expressed Genes and Signaling Pathways between XY and YY Testis in Yellow Catfish. [PDF]

open access: yesPLoS ONE, 2015
YY super-males have rarely been detected in nature and only been artificially created in some fish species including tilapia and yellow catfish (Pelteobagrusfulvidraco), which provides a promising model for testis development and spermatogenesis.
Junjie Wu   +6 more
doaj   +1 more source

Spermatogonial stem cells as a source for regenerative medicine

open access: yesMiddle East Fertility Society Journal, 2012
Several researchers have reported the derivation of multipotent cells from both mouse and human spermatogonial stem cells. These spermatogonia-derived stem cells show similarities with embryonic stem cells both for phenotype and functionality, indicating
Liang Ning   +4 more
doaj   +1 more source

Y/X-Chromosome-Bearing Sperm Shows Elevated Ratio in the Left but Not the Right Testes in Healthy Mice

open access: yesLife, 2021
The sex chromosomes play central roles in determining the sex of almost all of the multicellular organisms. It is well known that meiosis in mammalian spermatogenesis produces ~50% Y- and ~50% X-chromosome-bearing sperm, a 1:1 ratio. Here we first reveal
Chengqing Hu   +4 more
doaj   +1 more source

The Importance of Follow-Up and Evaluation of Intraoperative Findings to Determine Surgical Indications for Retractile Testis

open access: yesAdvances in Urology, 2023
Objectives. Ascending testis or acquired undescended testis develops in approximately 30% of cases of retractile testis, and orchiopexy is recommended for these cases.
Kazuro Kikkawa   +4 more
doaj   +1 more source

Larger testes are associated with a higher level of polyandry, but a smaller ejaculate volume, across bushcricket species (Tettigoniidae) [PDF]

open access: yes, 2010
While early models of ejaculate allocation predicted that both relative testes and ejaculate size should increase with sperm competition intensity across species, recent models predict that ejaculate size may actually decrease as testes size and sperm ...
Darren J. Parker   +3 more
core   +3 more sources

Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study [PDF]

open access: yes, 2019
Research question Does recombinant human vascular endothelial growth factor (VEGF-165) improve the efficiency of human immature testis tissue (ITT) xenotransplantation?
Goossens, Ellen   +5 more
core   +1 more source

Supernumerary Testis

open access: yesJournal of Radiology Case Reports, 2009
Polyorchidism is a rare congenital anomaly of the genital tract in which more than two testes are present, usually within the scrotum. Less than 100 cases of polyorchidism have been reported in medical literature till date. The most common form is the presence of three testis referred as triorchidism or tritestis.
Jaiger, Chintamani   +3 more
openaire   +2 more sources

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