Background Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) is only 12%, the ...
Prashant Kadam+5 more
doaj +1 more source
Comparative Transcriptome Analysis of Differentially Expressed Genes and Signaling Pathways between XY and YY Testis in Yellow Catfish. [PDF]
YY super-males have rarely been detected in nature and only been artificially created in some fish species including tilapia and yellow catfish (Pelteobagrusfulvidraco), which provides a promising model for testis development and spermatogenesis.
Junjie Wu+6 more
doaj +1 more source
The sex chromosomes play central roles in determining the sex of almost all of the multicellular organisms. It is well known that meiosis in mammalian spermatogenesis produces ~50% Y- and ~50% X-chromosome-bearing sperm, a 1:1 ratio. Here we first reveal
Chengqing Hu+4 more
doaj +1 more source
Effect of competitive cues on reproductive morphology and behavioral plasticity in male fruitflies [PDF]
Phenotypic plasticity will be favored whenever there are significant fitness benefits of responding to environmental variation. The extent and nature of the plasticity that evolves depends on the rate of environmental fluctuations and the capacity to ...
Bretman, Amanda+3 more
core +4 more sources
Testicular endocrine activity is upregulated by D-Aspartic acid in the green frog Rana esculenta [PDF]
This study investigated the involvement of D-aspartic acid (D-Asp) in testicular steroidogenesis of the green frog Rana esculenta and its effect on stimulation of thumb pad morphology and glandular activity, a typical testosterone-dependent secondary ...
ASSISI, LOREDANA+5 more
core +1 more source
Spermatogonial stem cells as a source for regenerative medicine
Several researchers have reported the derivation of multipotent cells from both mouse and human spermatogonial stem cells. These spermatogonia-derived stem cells show similarities with embryonic stem cells both for phenotype and functionality, indicating
Liang Ning+4 more
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Sperm competition and sperm midpiece size: no consistent pattern in passerine birds [PDF]
Sperm competition is thought to be a major force driving the evolution of sperm shape and function. However, previous studies investigating the relationship between the risk of sperm competition and sperm morphometry revealed inconclusive results and ...
Birkhead T.R+3 more
core +2 more sources
Larger testes are associated with a higher level of polyandry, but a smaller ejaculate volume, across bushcricket species (Tettigoniidae) [PDF]
While early models of ejaculate allocation predicted that both relative testes and ejaculate size should increase with sperm competition intensity across species, recent models predict that ejaculate size may actually decrease as testes size and sperm ...
Darren J. Parker+3 more
core +3 more sources
Plasma and testicular testosterone levels, volume density and number of Leydig cells and spermatogenic efficiency of rabbits [PDF]
Plasma and tissue testosterone concentrations were determined by radioimmunoassay in 12 eight-month-old sexually mature New Zealand White rabbits and evaluated for possible associations with spermatogenic efficiency as well as with volume density and ...
Berndtson, William E.+2 more
core +2 more sources
Young boys undergoing gonadotoxic treatments are at high risk of spermatogonial stem cell (SSC) loss and fertility problems later in life. Stem cell loss can also occur in specific genetic conditions, eg, Klinefelter syndrome (KS).
Aude Braye+2 more
doaj +1 more source