Results 41 to 50 of about 155,183 (266)
Advanced Healthcare Materials, EarlyView.An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone +4 more
wiley +1 more source
Dexime: A Selectively Enzyme‐Degradable Hydrogel for Protein Therapeutic Release
Advanced Materials, EarlyView.A dextrin‐oxime hydrogel (dexime) is produced using ketone or aldehyde modified dextrin and tetra‐oxyamine modified poly(ethylene glycol). The rheological and mechanical properties of dexime are tunable. Dexime is injectable, cytocompatible, hydrolytically stable, and selectively degradable by α‐amylase.
Quinton E. A. Sirianni +5 more
wiley +1 more source
Testis tumor associated to microlithiasis
Revista Paulista de Pediatria, 2013 OBJECTIVE: To discuss the relationship between testicular microlithiasis and testis tumors in children and to consider the chances of testis preserving surgery in specific cases.
Lisieux Eyer de Jesus +4 more
doaj +1 more source
Journal of Radiology Case Reports, 2009 Polyorchidism is a rare congenital anomaly of the genital tract in which more than two testes are present, usually within the scrotum. Less than 100 cases of polyorchidism have been reported in medical literature till date. The most common form is the presence of three testis referred as triorchidism or tritestis.
Jaiger, Chintamani +3 more
openaire +2 more sources
Advanced Materials, EarlyView.Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
eLifeAlthough the impact of gender-affirming hormone therapy (GAHT) on spermatogenesis in trans women has already been studied, data on its precise effects on the testicular environment is poor.
Emily Delgouffe +8 more
doaj +1 more source
Gene Expression of E2F1 in Chicken and Mouse Testes at Various Developmental Stages
The Journal of Poultry Science, 2010 E2F1 (Adenoviral E2 promoter binding transcription factor 1), mediating cell proliferation and p53-dependent/independent apoptosis, has been shown to be involved in spermatogenesis in mouse testis.
Heba A. Basha +3 more
doaj +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Advanced Science, EarlyView.The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source