Results 51 to 60 of about 217,852 (306)
Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
The computational analysis of human testis transcriptome reveals closer ties to pluripotency
Journal of Human Reproductive Sciences, 2012 Aims: The purpose of this study was to identify the differentially expressed genes (DEG) in human testis and also evaluate the relationship between human testis, human Embryonic Stem Cells (hESC), mouse testis and mouse ESCs (mESC).
M T Anand, Burra VLS Prasad
doaj +1 more source
Advanced Science, EarlyView.Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu +9 more
wiley +1 more source
Dysregulation of angiogenesis-specific signalling in adult testis results in xenograft degeneration
Scientific Reports, 2017 Ectopic xenografting of testis is a feasible option for preservation of male fertility and angiogenesis plays a pivotal role in xenograft survival and functionality.
Lalitha Devi +2 more
doaj +1 more source
Laboratory Animal Research, 2016 Descending of the testes is an important process for spermatogenesis and cryptorchidism is one of the most relevant genital defects in dogs. In a previous study, we observed abnormal morphology and proliferation of Sertoli cells in a cryptorchid testis ...
Hyo Young Jung +7 more
doaj +1 more source
Advanced Science, EarlyView.A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang +4 more
wiley +1 more source
Triorchidism: presenting as undescended testis in a case of indirect inguinal hernia
Clinics and Practice, 2016 Triorchidism is the commonest variety of polyorchidism, an entity with more than two testis is an extremely rare congenital anomaly of the testis. Although excision of the abnormal testis is a safer alternative proposed, recent literature suggests more ...
Ajay H. Bhandarwar +5 more
doaj +1 more source
Cells, 2021 The creation of a testis organoid (artificial testis tissue) with sufficient resemblance to the complex form and function of the innate testis remains challenging, especially using non-rodent donor cells.
Tat-Chuan Cham +3 more
doaj +1 more source
Cancer, 1970 The prognosis for lymphoma clinically localized to the testis at the time of original diagnosis is relatively favorable after orchiectomy and radiation therapy to the regional lymph nodes the previously held belief that life expectancy is poor for men with testicular lymphoma was due to failure in most reports to separate survival of those with ...
J M, Kiely +3 more
openaire +2 more sources
Advanced Science, EarlyView.In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu +16 more
wiley +1 more source