Results 71 to 80 of about 279,657 (361)

A Novel Cultivation System for Germ Cell Proliferation and Sustaining Whole Testicular Niche

Advanced Science, EarlyView.
A hydrogel microneedle‐based system enables whole testicular cultivation, supporting spermatogonial proliferation and enhancing spermatogenesis in vitro. This ‘whole testicular spermatogonia pool’ (WTSP) significantly increases spermatid production and fertility potential in mice. This system also promotes spermatogonial expansion in human fetal testes,
Yu Xia, Xiaoxuan Zhang, Bohang Zhang, Minhui Lu, Qing Cheng, Li Liu, Lifang Shi, Yiqiang Cui, Dingdong Chen, Laihua Li, Xuejiang Guo, Jingtao Guo, Jiahao Sha, Yuanjin Zhao, Yan Yuan   +14 more
wiley   +1 more source

Cancer testis antigens in newly diagnosed and relapse multiple myeloma: prognostic markers and potential targets for immunotherapy

Haematologica, 2011
Background In multiple myeloma, expression of cancer testis antigens may provide prognostic markers and potential targets for immunotherapy. Expression at relapse has not yet been evaluated for a large panel of cancer testis antigens which can be ...
Mark van Duin, Annemiek Broyl, Yvonne de Knegt, Hartmut Goldschmidt, Paul G. Richardson, Wim C. J. Hop, Bronno van der Holt, Debora Joseph-Pietras, George Mulligan, Rachel Neuwirth, Surinder S. Sahota, Pieter Sonneveld   +11 more
doaj   +1 more source

Dissent of the testis [PDF]

BMJ, 2007
We previously reported that two chocolates—Teasers and Truffles (Celebrations, Masterfoods UK, Melton Mowbray)—were strikingly similar to the 8 ml bead of the orchidometer used to assess testicular volume.1 We therefore suggested that they could be used to stage puberty in males and, because of their wide availability and low cost, commended their use.
Williams, Gareth, Dharmaraj, P
openaire   +3 more sources

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

PENGARUH PEMBERIAN BORAKS PERORAL SUB AKUT TERHADAP TERJADINYA ATROFI TESTIS TIKUS PUTIH JANTAN (RATTUS NOVERGICUS STRAIN WISTAR)

Saintika Medika, 2017
Pengaruh Pemberian Boraks Peroral Sub Akut Terhadap Terjadinya Atrofi Testis Tikus Putih Jantan (Rattus novergicus strain wistar). Latar Belakang: Penggunaan boraks banyak disalahgunakan pada makanan.
Diana Mayasari, Nanang Mardiroharjo
doaj   +1 more source

Draper‐ATG3 Interaction Positively Regulates Autophagy to Mediate Silk Gland Degradation in Bombyx mori

Advanced Science, EarlyView.
Draper is evolutionarily conserved across most insect species. Loss of Draper inhibits autophagy activation, delaying middle silk gland degradation in the silkworm during metamorphosis. Draper interacts with autophagy ‐ related protein 3 (ATG3) to orchestrate autophagosome formation—a process essential for silk gland degradation during the larval‐pupal
Shiyu Zou, Yuhan Luo, Yue Jin, Wenhui Jing, Yuxin Huang, Yanting Liang, Yinghui Li, Zhihua Hao, Yusong Xu, Huabing Wang   +9 more
wiley   +1 more source

EFEK ANTIMIKROBA EKSTRAK RIMPANG KUNYIT (CURCUMA DOMESTICA) TERHADAP ESCHERICHIA COLI SECARA IN VITRO

Saintika Medika, 2017
Pengaruh Pemberian Boraks Peroral Sub Akut Terhadap Terjadinya Atrofi Testis Tikus Putih Jantan (Rattus novergicus strain wistar). Latar Belakang: Penggunaan boraks banyak disalahgunakan pada makanan.
Resa Putra Adiputra, Irma Suswati, Fathiyah S   +2 more
doaj   +1 more source

Norepinephrine Induces Sertoli Cell Ferroptosis via Receptors Desensitization Causing Stress‐Related Male Reproductive Dysfunction

Advanced Science, EarlyView.
Psychological stress activates the sympathetic–adrenal axis, elevating norepinephrine (NE) and suppressing reproductive hormones, thereby impairing male reproduction. Excess NE overactivates and desensitizes β‐adrenergic receptors (β‐ARs), triggering Sertoli cell ferroptosis and disrupting spermatogenesis.
Lingyu Zhang, Shanfeng Gao, Xiaofan Xiong, Xin Liu, Rufeng Li, Xia Wang, Lin Han, Xuan Xiao, Xiaofei Wang, Wen Li, Yongxia Chang, Yuefeng Du, Juan Yang   +12 more
wiley   +1 more source

The Significance of the Contralateral Testis Size Measurement with Ultrasonography in Predicting Monorchism in Boys with Nonpalpable Testicles

Journal of Urological Surgery, 2017
Objective: The aim of this study was to determine the significance of contralateral testis size in predicting monorchism in pediatric patients with unilateral undescended testis.
Çağrı Akın Şekerci, Yılören Tanıdır, Tarık Emre Şener, Ruslan Asadov, Ahmet Şahan, Tufan Tarcan, Ferruh Şimsek, Cem Akbal   +7 more
doaj   +1 more source

Building the mammalian testis: origins, differentiation, and assembly of the component cell populations

Genes & Development, 2013
Testis development in the mammalian embryo requires the formation and assembly of several cell types that allow these organs to achieve their roles in male reproduction and endocrine regulation.
T. Svingen, P. Koopman
semanticscholar   +1 more source