Results 141 to 150 of about 169,506 (312)

Chemometrics-aided Surface-enhanced Raman spectrometric detection and quantification of GH and TE hormones in blood [PDF]

open access: yesarXiv
This work explores the use of Surface-Enhanced Raman Spectroscopy (SERS) combined with artificial neural network (ANN) models to detect and quantify growth hormone (GH) and testosterone (TE) in the blood of Sprague Dawley (SD) rats. SERS spectra were recorded from blood samples of SD rats injected with GH, TE, both hormones, and non-injected controls ...
arxiv  

A correlative biomarker study and integrative prognostic model in chemotherapy‐naïve metastatic castration‐resistant prostate cancer treated with enzalutamide

open access: yesThe Prostate, Volume 83, Issue 4, Page 376-384, March 2023., 2023
Abstract Background There is a considerable need to incorporate biomarkers of resistance to new antiandrogen agents in the management of castration‐resistant prostate cancer (CRPC). Methods We conducted a phase II trial of enzalutamide in first‐line chemo‐naïve asymptomatic or minimally symptomatic mCRPC and analyzed the prognostic value of TMPRSS2‐ERG
María P. Fernandez‐Perez   +30 more
wiley   +1 more source

Functional, pathogenic, and pharmacological roles of protein folding intermediates

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView., 2023
Abstract Protein expression and function in eukaryotic cells are tightly harmonized processes modulated by the combination of different layers of regulation, including transcription, processing, stability, and translation of messenger RNA, as well as assembly, maturation, sorting, recycling, and degradation of polypeptides.
Emiliano Biasini, Pietro Faccioli
wiley   +1 more source

SYNTHESIS AND METABOLIC STUDIES OF 17-METHYL-C14-TESTOSTERONE

open access: hybrid, 1954
Paul M. Hyde   +3 more
openalex   +1 more source

Delivery of Natural Small Molecules Through Nanocarriers for Cancer Treatment

open access: yesFood Frontiers, EarlyView.
Natural small molecules through nanocarriers for cancer treatment ABSTRACT Cancer is a formidable adversary, accounting for the second highest number of fatalities worldwide. A multitude of studies have indicated that naturally sourced small‐molecule compounds, owing to their low toxicity and multi‐target capabilities, significantly aid in the fight ...
Fangting Ye   +7 more
wiley   +1 more source

X‐linked ichthyosis: New insights into a multi‐system disorder

open access: yesSkin Health and Disease, Volume 2, Issue 4, December 2022., 2022
X‐linked ichthyosis is a rare genetic skin condition. We discuss here how it is also associated with multiple medical conditions which may impact affected individuals' education, quality of life and mortality. Awareness and understanding of these comorbidities will be important for ensuring the best multidisplinary care for individuals with XLI ...
Georgina H. Wren, William Davies
wiley   +1 more source

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