Results 101 to 110 of about 1,324 (186)

Cryopreservation of Spermatozoa Prior and Post‐Orchiectomy in Patients With Testicular Germ Cell Cancer—Does the Timing Matter?

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell cancer (TGCC) is the most frequent malignancy in young men of reproductive age. According to guidelines, semen cryopreservation should be performed prior to orchiectomy. Lack of time and local facilities as well as mental pressure are challenges in terms of fertility preservation before surgery.
Yuhe Tang, Gerald Pühse, Sabine Kliesch, Jann‐Frederik Cremers, Maria Schubert   +4 more
wiley   +1 more source

Neurotransmitter Systems Affected by PBDE Exposure: Insights from In Vivo and In Vitro Neurotoxicity Studies. [PDF]

Toxics
García-Suastegui WA, Navarro-Mabarak C, Silva-Adaya D, Dolores-Raymundo HG, Alvarez-Gonzalez MY, León-Olea M, Ramos-Chávez LA.   +6 more
europepmc   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Associations of internal persistent organic pollutant levels with sex hormones: An analysis by sex and menopausal status in a Spanish cohort. [PDF]

iScience
Pérez-Díaz C, Echeverría R, Pérez-Carrascosa FM, Salcedo-Bellido I, Requena P, Barrios-Rodríguez R, Ramos JJ, Olea N, Fernández MF, Martín-Olmedo P, Arrebola JP.   +10 more
europepmc   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Adulteration of Sports Supplements with Anabolic Steroids-From Innocent Athlete to Vicious Cheater. [PDF]

Nutrients
Puscasiu D, Flangea C, Vlad D, Popescu R, Vlad CS, Barac S, Rata AL, Marina C, Cobec IM, Laitin SMD.   +9 more
europepmc   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

Oxandrolone for burn patients: a systematic review and updated meta-analysis of randomized controlled trials from 2005 to 2025. [PDF]

World J Emerg Surg
Lou J, Xiang Z, Zhu X, Song J, Huang N, Li J, Jin G, Fan Y, Cui S.   +8 more
europepmc   +1 more source

Impact of FSHB and FSHR Genes Polymorphisms on Hormonal Profile and Sperm Retrieval Outcome in Men With Klinefelter Syndrome: A Clinical–Genetic Predictive Study

Andrology, EarlyView.
ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani, Giuseppe Grande, Maria Santa Rocca, Massimo Iafrate, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +6 more
wiley   +1 more source

Screening persistent organic pollutants for effects on testosterone and estrogen synthesis at human-relevant concentrations using H295R cells in 96-well plates. [PDF]

Cell Biol Toxicol
Strand D, Nylander E, Höglund A, Lundgren B, Martin JW, Karlsson O.   +5 more
europepmc   +1 more source