Results 41 to 50 of about 20,312 (267)

Nitric oxide modulates ATP-evoked currents in mouse Leydig cells

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Testosterone synthesis within Leydig cells is a calcium-dependent process. Intracellular calcium levels are regulated by different processes including ATP-activated P2X purinergic receptors, T-type Ca2+ channels modulated by the luteinizing hormone, and ...
J.L. de Deus   +2 more
doaj   +1 more source

Synaptic long-term potentiation and depression in the rat medial vestibular nuclei depend on neural activation of estrogenic and androgenic signals. [PDF]

open access: yesPLoS ONE, 2013
Estrogenic and androgenic steroids can be synthesised in the brain and rapidly modulate synaptic transmission and plasticity through direct interaction with membrane receptors for estrogens (ERs) and androgens (ARs).
Mariangela Scarduzio   +3 more
doaj   +1 more source

Hedgehog Signalling in Androgen Independent Prostate Cancer [PDF]

open access: yes, 2008
Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis.
Bisson, Isabelle   +7 more
core   +1 more source

Falsely elevated serum testosterone measurements resulting from testosterone topical gel contamination of the venipuncture site: Case Series and retrospective review

open access: yesHeliyon, 2023
Testosterone as replacement therapy for male hypogonadism or as gender-affirming hormone therapy for transgender and non-binary patients has increased worldwide.
Aranza Pinedo Pichilingue   +2 more
doaj  

Advances in hormone replacement therapy: making the menopause manageable

open access: yesBMC Women's Health, 2008
The importance of the results of some large, randomized controlled trials (RCTs) on Hormone Replacement Therapy (HRT) has modified the risk/benefit perception of HRT. Recent literature review supports a different management.
Palacios Santiago
doaj   +1 more source

Neurosteroids as Selective Inhibitors of Glycine Receptor Activity: Structure-Activity Relationship Study on Endogenous Androstanes and Androstenes

open access: yesFrontiers in Molecular Neuroscience, 2020
The ability of androstane and androstene neurosteroids with modifications at C-17, C-5, and C-3 (compounds 1-9) to influence the functional activity of inhibitory glycine and γ-aminobutyric acid (GABA) receptors was estimated.
Julia V. Bukanova   +2 more
doaj   +1 more source

Male and female sex hormones in primary headaches [PDF]

open access: yes, 2018
Background: The three primary headaches, tension-type headache, migraine and cluster headache, occur in both genders, but all seem to have a sex-specific prevalence.
Alberto Terrin   +9 more
core   +1 more source

A correlative biomarker study and integrative prognostic model in chemotherapy‐naïve metastatic castration‐resistant prostate cancer treated with enzalutamide

open access: yesThe Prostate, Volume 83, Issue 4, Page 376-384, March 2023., 2023
Abstract Background There is a considerable need to incorporate biomarkers of resistance to new antiandrogen agents in the management of castration‐resistant prostate cancer (CRPC). Methods We conducted a phase II trial of enzalutamide in first‐line chemo‐naïve asymptomatic or minimally symptomatic mCRPC and analyzed the prognostic value of TMPRSS2‐ERG
María P. Fernandez‐Perez   +30 more
wiley   +1 more source

Heterogeneity, leveling the playing field, and affirmative action in contests

open access: yesSouthern Economic Journal, Volume 89, Issue 3, Page 924-974, January 2023., 2023
Abstract The heterogeneous abilities of players in various competitive contexts often lead to undesirable outcomes such as low effort provision, a lack of diversity, and inequality. A range of policies is implemented to mitigate such issues by enforcing competitive balance, that is, by leveling the playing field.
Subhasish M. Chowdhury   +2 more
wiley   +1 more source

An update on the potential for male contraception : emerging options [PDF]

open access: yes, 2013
The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Alsaadi, Manal   +5 more
core   +1 more source

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